CESARE R VALERI, M.D.
Medical Practice at Ocean Ave, Marblehead, MA

4804363, Feb 14, 1989

Jul 16, 1986

6/886196

Cesare R. Valeri - Marblehead MA

Autologous Blood Corporation - Miami FL

A61M 3700

604 6

This disclosure relates to a blood processing and preservation system. Apparatus of the system comprises a primary collection bag, a blood collection tube connected to the bag and adapted to draw a unit of blood from a person and feed the blood into the bag, and a harness connected to the bag for conducting solutions and blood components into and out of the bag. The harness includes a first tube for removing at least one blood component from the bag while retaining another component, a second tube for moving a cryoprotective solution into and out of the bag, a third tube for conducting a wash solution into and out of the bag, and identification on the bag. The foregoing apparatus is usable in a blood system including the method steps of collecting a unit of blood from a person and delivering the blood to the collection bag, processing the blood to separate the components and removing the components except for the red blood cells from the bag, preparing the red blood cells for freezing by conducting a cryoprotective solution into the bag and mixing this solution with the red blood cells, preserving the red blood cells by freezing, subsequently washing the red blood cells by conducting a wash solution and the cells into and out of the bag, and delivering the cells in the same collection bag to a recipient. While the foregoing method may be used in a homologous blood system where the recipient is not the donor, it is especially suited for use in an autologous blood system where the blood is reinfused in the person who furnished the blood, and the identification on the bag assures the recipient that he/she is receiving his/her own blood. Other blood components, such as the plasma, may also be preserved by freezing.

RE33924, May 12, 1992

Dec 14, 1990

7/627405

Cesare R. Valeri - Marblehead MA

Autologous Blood Corp. - Miami FL

A61M 3700

604 6

This disclosure relates to a blood processing and preservation system. Apparatus of the system comprises a primary collection bag, a blood collection tube connected to the bag and adapted to draw a unit of blood from a person and feed the blood into the bag, and a harness connected to the bag for conducting solutions and blood components into and out of the bag. The harness includes a first tube for removing at least one blood component from the bag while retaining another component, a second tube for moving a cryoprotective solution into and out of the bag, a third tube for conducting a wash solution into and out of the bag, and identification on the bag. The foregoing apparatus is usable in a blood system including the method steps of collecting a unit of blood from a person and delivering the blood to the collection bag, processing the blood to separate the components and removing the components except for the red blood cells from the bag, preparing the red blood cells for freezing by conducting a cryoprotective solution into the bag and mixing this solution with the red blood cells, preserving the red blood cells by freezing, subsequently washing the red blood cells by conducting a wash solution and the cells into and out of the bag, and delivering the cells in the same collection bag to a recipient. . [. While the. ]. . Iadd. The. Iaddend. foregoing method may be used in a homologous blood system where the recipient is not the donor,. [. it is especially suited for use. ]. . Iadd. or. Iaddend.

5585361, Dec 17, 1996

Jun 7, 1994

8/255252

James W. Burns - Boston MA
Cesare R. Valeri - Marblehead MA

Genzyme Corporation - Framingham MA
The Trustees of Boston University - Boston MA

A61K 3170

514 25

Methods of preventing or treating thrombotic conditions by administering pharmaceutical compositions containing hyaluronic acid are described.