Inventors:
Kenneth W. Lyles - Durham NC, US
Cathleen S. Colon-Emeric - Durham NC, US
Christopher M. O'Connor - Durham NC, US
Richard S. Stack - Chapel Hill NC, US
Colleen Stack - Chapel Hill NC, US
International Classification:
A61K 31/675, A61P 9/00, C07F 9/40
Abstract:
The present invention provides for methods and compositions for treating and/or preventing cardiac dysfunction by administering to subject a therapeutically effective amount of a bisphosphonate, functional analogue or a pharmaceutically effective salt thereof.