CATALIN TOMA, MD
Osteopathic Medicine at Lothrop St, Pittsburgh, PA

8460269, Jun 11, 2013

Sep 13, 2010

12/880807

Catalin Toma - Pittsburgh PA, US
Flordeliza Villanueva - Pittsburgh PA, US
William Richard Wagner - Wexford PA, US
Joon S. Lee - Pittsburgh PA, US
Jianjun Wang - Glenshaw PA, US
Xucai Chen - Glenshaw PA, US
Andrew Fisher - Pittsburgh PA, US

University of Pittsburgh—Of the Commonwealth System of Higher Education - Pittsburgh PA

A61M 31/00

604500, 604 22, 435177, 424 937, 424723

The disclosed technology describes compositions and methods useful for providing cell based therapy. For example, one embodiment of cell based therapy involves the regeneration of injured tissue and/or promoting wound healing. Certain embodiments provide improved therapeutic compositions using microbubbles by delivering biological progenitor cells to the injured tissues. The administration of the microbubbles is directed by acoustic radiation forces that interact with embodiments of microbubbles comprising an acoustically active gas. As such, a high efficiency of progenitor cell delivery to injured tissue is realized. One advantage of this technique over targeted delivery of pharmaceutical compounds, is that the delivered progenitors cells may be derived from the patient (i. e. , personalized therapy), thereby avoiding side effects, allergic reactions, and overall problems associated with refractive drug responses.

2008028, Nov 13, 2008

Apr 2, 2008

12/061562

George Oliviu Angheloiu - Dubois PA, US
William D. Anderson - Pittsburgh PA, US
Catalin Toma - Pittsburgh PA, US

University of Pittsburgh - Of the Commonwealth System of Higher Education - Pittsburgh PA

A61M 1/34, A61M 25/00

604 609, 604523

The invention provides a system and a method for removal of contrast from blood. In one aspect, the invention provides a catheter for removal of contrast from the veins that drain the cerebral circulation. In a second aspect, the invention provides a method for removing contrast from blood by contacting the blood with a sorbent.

2013019, Aug 1, 2013

Mar 14, 2013

13/804989

University of Pittsburgh - Of the Commonwealth System of Higher Education - Pittsburgh PA, US
John A. Kellum - Pittsburgh PA, US
William D. Anderson - Pittsburgh PA, US
Catalin Toma - Pittsburgh PA, US

University of Pittsburgh - Of the Commonwealth System of Higher Education - Pittsburgh PA

A61M 1/34, A61M 25/10, A61M 25/00

604 504, 604523, 604 9601

In one aspect, the invention provides a device comprising a catheter. In another aspect, the invention provides a method of removing an agent from blood.