Inventors:
Maria Athanasiou - Fond du Lac WI, US
Kerri Holick - Brookfield CT, US
Carol Reed - Bethany CT, US
Benjamin Salisbury - Dayton OH, US
Alessandro Serretti - Bologna, IT
Wei Zou - New Haven CT, US
International Classification:
A61K 31/497, C12Q 1/68
Abstract:
Markers of the ACE, ATP5C3, BCL2L1, CYP2C9, DRD3, FOS, DTNBP1, GABRG3, GRIA4, LAMA4, MAPK1, NPY1R, OPRD1, OPRM1, PER3, PLCB1, PSMD1, ABI1, LOC402382, and NCALD genes, and their association with response to antidepressants are disclosed. Compositions and methods for detecting and using these markers in a variety of clinical applications are disclosed.