Inventors:
David A. Ostrov - Gainesville FL, US
Carmen J. Allegra - Gainesville FL, US
Assignee:
University of Florida Research Foundation - Gainesville FL
International Classification:
A61K 35/12, A61K 31/198, A61K 31/70, A61K 31/505
US Classification:
424573, 435 614, 4241551, 4241741, 4241411, 514129, 51425212, 514274, 514345, 514562, 562430, 562456, 562557, 562594
Abstract:
The present invention relates to compounds as novel thymidylate synthase inhibitors, novel strategies to treat or prevent neoplasia in a subject, methods and compositions thereof.