CARLOS M. ISALES, MD
Osteopathic Medicine at 15 St, Augusta, GA
License number
Georgia 038018
Category
Osteopathic Medicine
Type
Endocrinology, Diabetes & Metabolism
Address
Address
1120 15Th St, Augusta, GA 30912
Phone
(706) 721-2131
(706) 721-1459 (Fax)
(706) 828-8402
(706) 721-1459 (Fax)
(706) 828-8402
Organization information
See more information about CARLOS M. ISALES at bizstanding.comMCG Health Care - Carlos M Isales MD
1467 Harper St #HB5025, Augusta, GA 30901
Categories:
Endocrinology & Metabolism Physicians & Surgeons, Physicians & Surgeons
Phone:
(706) 721-2131 (Phone)
Professional information
Dr. Carlos M Isales, Augusta GA - MD (Doctor of Medicine)
Specialties:
Endocrinology, Diabetes & Metabolism, Endocrinology & Metabolism
Address:
Georgia Regents University
1120 15Th St STE HB5025, Augusta 30912
(706) 721-2131 (Phone)
1120 15Th St STE HB5025, Augusta 30912
(706) 721-2131 (Phone)
Certifications:
Diabetes, Metabolism & Endocrinology, 1987, Internal Medicine, 1985
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
Georgia Regents University
1120 15Th St STE HB5025, Augusta 30912
Georgia Regents Medical Center
1120 15Th Street Ext, Augusta 30912
1120 15Th St STE HB5025, Augusta 30912
Georgia Regents Medical Center
1120 15Th Street Ext, Augusta 30912
Education:
Medical School
University of Puerto Rico / Medical Sciences Campus
Graduated: 1982
San Juan Va Hosp
Yale New Haven Hospital
University of Puerto Rico / Medical Sciences Campus
Graduated: 1982
San Juan Va Hosp
Yale New Haven Hospital
Carlos M Isales, Augusta GA
Specialties:
Endocrinologist
Address:
1499 Walton Way, Augusta, GA 30901
1120 15Th St, Augusta, GA 30912
Limited To Official University Duties On, Augusta, GA 30912
1120 15Th St, Augusta, GA 30912
Limited To Official University Duties On, Augusta, GA 30912
Education:
University of Puerto Rico, School of Medicine - Doctor of Medicine
Yale New Haven Psychiatric Hospital - Fellowship - Endocrinology
VA Medical Center - San Juan - Residency - Internal Medicine
Yale New Haven Psychiatric Hospital - Fellowship - Endocrinology
VA Medical Center - San Juan - Residency - Internal Medicine
Board certifications:
American Board of Internal Medicine Certification in Internal Medicine, American Board of Internal Medicine Sub-certificate in Endocrinology and Metabolism (Internal Medicine)
Carlos M Isales, Augusta GA
Specialties:
Internal Medicine, Endocrinology and Metabolism, Endocrinology, Diabetes & Metabolism
Work:
2ND Floor
1447 Harper St, Augusta, GA 30912 Medical College of Georgia
1120 15Th St, Augusta, GA 30912
1447 Harper St, Augusta, GA 30912 Medical College of Georgia
1120 15Th St, Augusta, GA 30912
Education:
University of Puerto Rico (1982)
Professor At Georgia Health Sciences University
Location:
Augusta, Georgia Area
Industry:
Higher Education
Glucose-Dependent Insulinotropic Peptide For Use As An Osteotropic Hormone
US Patent:
6410508, Jun 25, 2002
Filed:
Oct 7, 1999
Appl. No.:
09/414189
Inventors:
Carlos M. Isales - Augusta GA 30909
Roni J. Bollag - Martinez GA 30907
Howard Rasmussen - Augusta GA 30909
Roni J. Bollag - Martinez GA 30907
Howard Rasmussen - Augusta GA 30909
International Classification:
A01N 3718
US Classification:
514 2, 514 3, 514 12, 530303, 530308, 4241841, 4241981, 435 691, 435325, 435243
Abstract:
The examples demonstrate that GIP receptor mRNA and protein are present in normal bone and osteoblastic-like cell lines, and that high-affinity receptors for GIP can be demonstrated by I GIP binding studies. When applied to osteoblast-like cells (SaOS2), GIP stimulated an increase in cellular cAMP content and in intracellular calcium, with both responses being dose dependent. Moreover, administration of GIP results in elevated expression of collagen type I mRNA as well as an increase in alkaline phosphatase activity. Both of these effects reflect anabolic actions of presumptive osteoblasts. These results provide the first evidence that GIP receptors are present in bone and osteoblastic like cells and that GIP modulates the function of these cells. GIP has anabolic actions on remodeling bone, increasing vertebral bone density in a rat model of osteoporosis. GIP at 10 nM inhibits PTH-induced bone resorption in a fetal long bone assay and stimulates the synthesis of type 1 collagen mRNA.