CARL M REPPUCCI
Broker in North Andover, MA
License number
Massachusetts 9539627
Issued Date
Jan 7, 2016
Expiration Date
Feb 23, 2018
Type
Salesperson
Address
Address
North Andover, MA 01845
Professional information
Carl Reppucci - North Andover, MA
Work:
BioConcept Laboratories Inc
Product Development Scientist CPEX Pharmaceuticals Inc - Exeter, NH
Formulation Scientist / Research and Product Development Arthur D. Little Inc - Cambridge, MA
Research Assistant Toxikon Inc - Woburn, MA
Metals Analyst Morton International
Analytical Chemist/R&D Morton International - Danvers, MA Morton International
Production Chemist/R&D Morton International
Chemical Technician Stahl Finish Inc - Peabody, MA
Chemist Technician
Product Development Scientist CPEX Pharmaceuticals Inc - Exeter, NH
Formulation Scientist / Research and Product Development Arthur D. Little Inc - Cambridge, MA
Research Assistant Toxikon Inc - Woburn, MA
Metals Analyst Morton International
Analytical Chemist/R&D Morton International - Danvers, MA Morton International
Production Chemist/R&D Morton International
Chemical Technician Stahl Finish Inc - Peabody, MA
Chemist Technician
Education:
Merrimack College - North Andover, MA
B.S. in Chemistry Merrimack College - North Andover, MA
MS course in Intro to Systems Engineering
B.S. in Chemistry Merrimack College - North Andover, MA
MS course in Intro to Systems Engineering
Macrocyclic Formulations For Transmembrane Drug Delivery
US Patent:
2008010, May 8, 2008
Filed:
Nov 2, 2006
Appl. No.:
11/591788
Inventors:
Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
International Classification:
A61K 9/14
US Classification:
424486
Abstract:
Topically applied pharmaceutical products comprising (a) an active ingredient, (b) an organogel, and (c) a non-irritating permeation enhancer, are disclosed, along with and methods of use and formulations thereof. The topically applied products and methods are intended to be used to enhance any of the transdermal, subdermal, transmembrane, musculoskeletal, transungual, transonychial, and/or peronychial deliveries of a therapeutically effective amount of an active ingredient to a patient. The invention is particularly directed to topically applied pharmaceutical products for enhancing the delivery of a therapeutically effective amount of an active ingredient to a diseased or infected nail bed, nail matrix, and/or nail plate in the toenails or fingernails of a patient suffering from onychomycosis. The invention is also directed to delivery of an anti-inflammatory agent, preferably of the Cox-2 enzyme inhibitory class, topically to a site of soft tissue injury or discomfort.
Pharmaceutical Composition And Methods For Peptide Treatment
US Patent:
2014007, Mar 13, 2014
Filed:
Sep 11, 2013
Appl. No.:
14/024230
Inventors:
- Exeter, DE
Carl REPPUCCI - North Andover MA, US
Carl REPPUCCI - North Andover MA, US
International Classification:
A61K 9/00, A61K 47/22, A61K 9/107, A61K 38/08
US Classification:
514 113
Abstract:
Disclosed are compositions and methods for treating a patient with a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins, wherein the pharmaceutical composition is in the form of an emulsified nasal spray comprising: a macrocyclic permeation enhancer, a liquid carrier comprising water, and a therapeutically effective amount of a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins; wherein the macrocyclic permeation enhancer is a Hsieh enhancer emulsified in the liquid carrier.
Pharmaceutical Compositions And Methods For Peptide Treatment
US Patent:
8541359, Sep 24, 2013
Filed:
Sep 18, 2009
Appl. No.:
12/562974
Inventors:
Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
Assignee:
CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:
A61K 9/107, A61K 38/02
US Classification:
514 11, 514937, 514938
Abstract:
Disclosed are compositions and methods for treating a patient with a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins, wherein the pharmaceutical composition is in the form of an emulsified nasal spray comprising: a macrocyclic permeation enhancer, a liquid carrier comprising water, and a therapeutically effective amount of a pharmaceutically active agent other than insulin selected from the group consisting of peptides, peptidomimetics, and proteins; wherein the macrocyclic permeation enhancer is a Hsieh enhancer emulsified in the liquid carrier.
Fibrilliform-Free Insulin Composition
US Patent:
2008004, Feb 21, 2008
Filed:
Jun 8, 2007
Appl. No.:
11/811170
Inventors:
Robert Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Zhengmao Li - Newmarket NH, US
Carl Reppucci - North Andover MA, US
Zhengmao Li - Newmarket NH, US
International Classification:
A61K 38/28, A61M 11/00, A61P 3/08
US Classification:
514003000, 128200140
Abstract:
Compositions and methods are disclosed for treating a patient with insulin, wherein a composition in a form suitable for nasal delivery to a patient comprises a therapeutically effective amount of insulin, a permeation enhancer, a liquid carrier, and an acid present in said composition in an amount sufficient to provide an acidic pH, but not greater than a pH of 4.5, said acid being selected from the group consisting of: monovalent inorganic acid(s), sulfuric acid, and acetic acid. Preferably the composition is essentially-free of citrate(s) and essentially-free of phosphate(s). The composition being thus designed with the intent to provide a composition that is essentially-free of fibrilliform (or beta-sheet) insulin polymorphs.
Therapeutically Effective Preparations Of Insulin
US Patent:
2011009, Apr 28, 2011
Filed:
Oct 12, 2010
Appl. No.:
12/902397
Inventors:
Fred Feldman - Kensington NH, US
Zhengmao Li - Newmarket NH, US
Jeffrey Banas - Raymond NH, US
Carl Reppucci - North Andover MA, US
Zhengmao Li - Newmarket NH, US
Jeffrey Banas - Raymond NH, US
Carl Reppucci - North Andover MA, US
Assignee:
CPEX PHARMACEUTICALS, INC. - Exeter NH
International Classification:
A61K 38/28, A61K 9/107, A61P 3/10
US Classification:
424400, 514 59
Abstract:
The present invention provides a preparation of a therapeutically effective amount of insulin with a concentration of A21 desamido insulin greater than about 2% (w/w).
Pharmaceutical Compositions And Methods For Insulin Treatment
US Patent:
8044020, Oct 25, 2011
Filed:
Nov 6, 2009
Appl. No.:
12/614335
Inventors:
Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
International Classification:
A61K 38/00, A61K 47/00, A61K 38/28, A61K 51/00
US Classification:
514 12, 514 11, 514 67, 514 68, 514 69, 424 169
Abstract:
Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.
Pharmaceutical Compositions And Methods For Insulin Treatment
US Patent:
2009015, Jun 18, 2009
Filed:
Dec 18, 2008
Appl. No.:
12/337924
Inventors:
Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
Assignee:
CPEX PHARMACEUTICALS, INC. - Exeter NH
International Classification:
A61K 38/28
US Classification:
514 3
Abstract:
Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.
Pharmaceutical Compositions And Methods For Insulin Treatment
US Patent:
2005012, Jun 9, 2005
Filed:
Dec 2, 2004
Appl. No.:
11/002858
Inventors:
Robert Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
International Classification:
A61K038/28, A61L015/16
US Classification:
424448000, 514003000
Abstract:
Compositions and methods for treating a patient with insulin that combines insulin, a permeation enhancer, and a carrier that maintains an acidic pH, are disclosed.
Insulin Composition
US Patent:
7989419, Aug 2, 2011
Filed:
Jun 8, 2007
Appl. No.:
11/811169
Inventors:
Robert J. Gyurik - Exeter NH, US
Carl Reppucci - North Andover MA, US
Carl Reppucci - North Andover MA, US
Assignee:
CPEX Pharmaceuticals, Inc. - Exeter NH
International Classification:
A61K 38/28
US Classification:
514 59
Abstract:
Pharmaceutical compositions for nasal administration to humans, or to warm-blooded animals, comprise: (A) a therapeutically effective amount of insulin; (B) a permeation enhancer; and (C) a liquid carrier; the compositions being further comprised of, or characterized by, any, or each, of: (D) a combination of non-ionic surfactants; wherein the combination of non-ionic surfactants comprises: (i) at least one fatty acid ester of a sugar or sugar alcohol and (ii) at least one pegylated fatty acid ester of a sugar or sugar alcohol; (E) an acidic pH, but no greater than a pH of 4. 5; and (F) an osmolality of