MRS. BRIDGETTE ALEXANDROU, M.S., CCC-SLP
Speech Language Pathology at Usf Magnolia Dr, Tampa, FL
License number
Florida SA10016
Category
Speech Language Pathology
Type
Speech-Language Pathologist
Address
Address
12902 Usf Magnolia Dr, Tampa, FL 33612
Phone
(813) 745-8449
Personal information
See more information about BRIDGETTE ALEXANDROU at radaris.comName
Address
Phone
17735 Deerfield Dr, Lutz, FL 33558
Tampa, FL
14317 Brentwood Pl, Tampa, FL 33618
17735 Deerfield Dr, Lutz, FL 33558
2911 Burr Oak Dr, Tampa, FL 33618
Professional information
Bridgette Alexandrou, Tampa FL - MS (Mitral stenosis; also Master of Science or Medical scientist)
Specialties:
Speech-Language Pathology
Address:
12902 Usf Magnolia Dr, Tampa 33612
(813) 745-8449 (Phone)
(813) 745-8449 (Phone)
Languages:
English
Combination Of Insulin And Ascorbate To Enhance Wound Healing
US Patent:
2007028, Dec 6, 2007
Filed:
Jun 5, 2007
Appl. No.:
11/758080
Inventors:
Kurt Musselmann - Tampa FL, US
John R. Hassell - Tampa FL, US
Brad Kane - Lakeland FL, US
Bridgette Alexandrou - Tampa FL, US
John R. Hassell - Tampa FL, US
Brad Kane - Lakeland FL, US
Bridgette Alexandrou - Tampa FL, US
Assignee:
UNIVERSITY OF SOUTH FLORIDA - Tampa FL
International Classification:
A61K 38/28, A61K 31/665, A61K 31/375
US Classification:
514 3, 514101, 514474
Abstract:
Provided is a method of stimulating collagen synthesis and proteoglycan (lumican and keratocan) accumulation. Collagenase isolated keratocytes were cultured with or without insulin with or without ascorbate. Insulin stimulates the synthesis of collagen but does not affect the accumulation of lumican and keratocan. Insulin plus ascorbate, however, stimulates the synthesis of collagen and increased the accumulation of these proteoglycans. The accumulation of PGDS, a KSPG that does not interact with collagen, is not affected by ascorbate. Only the collagen made in the presence of ascorbate was pepsin resistant. EDB overrode the effects of ascorbate on pepsin resistance and proteoglycan accumulation.
Combination Of Insulin And Ascorbate To Enhance Wound Healing
US Patent:
2011002, Feb 3, 2011
Filed:
Oct 14, 2010
Appl. No.:
12/904489
Inventors:
Kurt Musselmann - Tampa FL, US
John R. Hassell - Tampa FL, US
Brad Kane - Lakeland FL, US
Bridgette Alexandrou - Tampa FL, US
John R. Hassell - Tampa FL, US
Brad Kane - Lakeland FL, US
Bridgette Alexandrou - Tampa FL, US
Assignee:
UNIVERSITY OF SOUTH FLORIDA - Tampa FL
International Classification:
C12N 5/02
US Classification:
435375
Abstract:
Provided is a method of stimulating collagen synthesis and proteoglycan (lumican and keratocan) accumulation. Collagenase isolated keratocytes were cultured with or without insulin with or without ascorbate. Insulin stimulates the synthesis of collagen but does not affect the accumulation of lumican and keratocan. Insulin plus ascorbate, however, stimulates the synthesis of collagen and increased the accumulation of these proteoglycans. The accumulation of PGDS, a KSPG that does not interact with collagen, is not affected by ascorbate. Only the collagen made in the presence of ascorbate was pepsin resistant. EDB overrode the effects of ascorbate on pepsin resistance and proteoglycan accumulation.