BRIAN RICHARD MACDONALD
Medical Practice in Valley Forge, PA
License number
Pennsylvania MD051963L
Category
Medicine
Type
Medical Physician and Surgeon
Address
Address
Valley Forge, PA 19481
Professional information
Method Of Treating Immune Cell Mediated Systemic Diseases
US Patent:
2001005, Dec 27, 2001
Filed:
Jul 13, 2001
Appl. No.:
09/905836
Inventors:
Peter Bugelski - Drexel Hill PA, US
Charles Davis - Devon PA, US
Brian MacDonald - Valley Forge PA, US
Charles Davis - Devon PA, US
Brian MacDonald - Valley Forge PA, US
Assignee:
SmithKline Beecham Corporation
International Classification:
A61K038/16, A61K039/395
US Classification:
514/008000, 424/131100
Abstract:
An improved method of treating immune cell mediated systemic diseases, particularly T and B cell mediated diseases, is provided by increasing the systemic exposure, or bioavailibility, of a therapeutic protein. Such therapeutic protein is selected from the group consisting of a monoclonal antibody, a soluble receptor and a soluble ligand which binds to an antigen expressed on the surface of an immunce cell.