Non-Invasive Detection Of Complement-Mediated Inflammation Using Cr2-Targeted Nanoparticles
US Patent:
2011028, Nov 24, 2011
Filed:
Feb 4, 2010
Appl. No.:
13/148028
Inventors:
Joshua M. Thurman - Greenwood Village CO, US Natalie Serkova - Denver CO, US Conrad Stoldt - Denver CO, US Brian Larsen - Denver CO, US
Assignee:
The Regents of the University of Colorado - Denver CO
International Classification:
A61K 49/16, A61P 37/00, A61K 49/08
US Classification:
424 9323, 424 932
Abstract:
Methods of non-invasive imaging of complement-mediated inflammation are provided. Compositions including CR-targeted ultrasmall superparamagnetic nanoparticles or aggregates thereof for use with those methods are also provided.