BRIAN M HEALEY
Plumbers in Scituate, MA
License number
Massachusetts 13019
Issued Date
Apr 18, 2000
Expiration Date
May 1, 2018
Type
Master Plumber
Address
Address
Scituate, MA 02066
Personal information
See more information about BRIAN M HEALEY at radaris.comName
Address
Phone
53 Huntington Rd, Arlington, MA 02474
4 Pheasantwood Dr, Wakefield, MA 01880
48 Tercentennial Dr, Billerica, MA 01821
3 Collier Avenue Ext, Scituate, MA 02066
7 Ascot St #3, Brighton, MA 02135
Professional information
See more information about BRIAN M HEALEY at trustoria.com
Antiproliferative Pyrimidyl, Fused Pyrimidyl And Pyrimidyl Hydrazones
Antiproliferative Pyrimidyl, Fused Pyrimidyl And Pyrimidyl Hydrazones
US Patent:
2012023, Sep 20, 2012
Filed:
May 31, 2012
Appl. No.:
13/484329
Inventors:
BRIAN HEALEY - Scituate MA, US
Zhong Zhao - Wayland MA, US
Amanda Sutton - Hingham MA, US
Matthias Schwarz - Gland (VD), CH
Zhong Zhao - Wayland MA, US
Amanda Sutton - Hingham MA, US
Matthias Schwarz - Gland (VD), CH
Assignee:
MERCK SERONO SA - Coinsins, Vaud
International Classification:
A61K 31/505, A61K 31/517, C07D 239/42, C07D 413/04, C12N 5/09, C07D 239/47, C07D 413/10, A61K 31/5377, C07D 401/04, A61P 35/00, C07D 239/94, A61K 31/506
US Classification:
5142358, 544293, 5142664, 544326, 514256, 544328, 544317, 514274, 544327, 544329, 544122, 435375
Abstract:
The present invention is related to a novel series of pyrimidyl or fused pyrimidyl hydrazones. Compounds of Formula (I) wherein A is selected from the group consisting of Formulas (A1), (A2), (A3), (A4), (A5) are useful for the treatment and/or prevention of a proliferative disease.
Methods For Identifying Modulators Of Active Kit Tyrosine Kinase Receptor
Methods For Identifying Modulators Of Active Kit Tyrosine Kinase Receptor
US Patent:
2007022, Sep 27, 2007
Filed:
Dec 6, 2004
Appl. No.:
10/579286
Inventors:
Julian Andreev - Weymouth MA, US
Brian Healey - Scituate MA, US
Peter Blume-Jensen - Newton MA, US
Stephen Arkinstall - Belmont MA, US
Rong Dong - Wellesley MA, US
Brian Healey - Scituate MA, US
Peter Blume-Jensen - Newton MA, US
Stephen Arkinstall - Belmont MA, US
Rong Dong - Wellesley MA, US
Assignee:
APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. - Curacao
International Classification:
A61K 31/00, C07K 16/00, G01N 33/567
US Classification:
514001000, 435007200, 435007210, 530387100
Abstract:
The present invention relates to cell-based assays useful for screening for modulators, such as inhibitors, of activated mutant KIT tyrosine kinase receptors, which are associated with mast cell-related disorders, such as mastocytosis and various types of cancer. The invention further provides for the treatment of mast cell-related disorders with an inhibitor identified by the screening method.
Antiproliferative Pyrimidyl, Fused Pyrimidyl And Pyrimidyl Hydrazones
Antiproliferative Pyrimidyl, Fused Pyrimidyl And Pyrimidyl Hydrazones
US Patent:
8288398, Oct 16, 2012
Filed:
Dec 8, 2006
Appl. No.:
12/096110
Inventors:
Brian Healey - Scituate MA, US
Zhong Zhao - Wayland MA, US
Amanda Sutton - Hingham MA, US
Matthias Schwarz - Gland, CH
Zhong Zhao - Wayland MA, US
Amanda Sutton - Hingham MA, US
Matthias Schwarz - Gland, CH
Assignee:
Merck Serono SA - Coinsins, Vaud
International Classification:
A01N 43/54, A61K 31/517
US Classification:
5142664, 544293
Abstract:
The present invention is related to a novel series of pyrimidyl or fused pyrimidyl hydrazones. Compounds of Formula (I) wherein A is selected from the group consisting of Formulas (A1), (A2), (A3), (A4), (A5) are useful for the treatment and/or prevention of a proliferative disease.