Inventors:
Brian Hjelle - Albuquerque NM
Steve Jenison - Albuquerque NM
Assignee:
The University of New Mexico - Albuquerque NM
International Classification:
C12N 1540
Abstract:
The invention provides HARDS virus rDNA for expression in molecular clones. The expressed products are useful in immunodiagnostics, prophylactics, and therapeutics for the HARDS virus and related hantaviruses. Of particular interest are a type-specific epitope of the HARDS virus G1 protein, and dominant epitopes of the HARDS virus N protein cross-reactive with antibodies to the HARDS virus and the related hantavirus PHV, both expressed by cDNA clones according to the invention.