Inventors:
David Myles - Kensington CA, US
Mark Burlingame - Oakland CA, US
Simon Shaw - San Francisco CA, US
Kurt Sundermann - Burlingame CA, US
Brian Freeze - Philadelphia PA, US
Ignacio Martin - Canary Islands, ES
Tomoyasu Hirose - Tokyo, JP
Amos Smith - Merion PA, US
International Classification:
C07F009/28
Abstract:
Synthetic methods and intermediates useful in the preparation of lactone containing compounds such as discodermolide and compounds which mimic the chemical or biological activity of discodermolide are provided.