Inventors:
Lianping XING - Webster NY, US
Brendan F. BOYCE - Pittsford NY, US
Edward M. SCHWARZ - Rochester NY, US
Assignee:
UNIVERSITY OF ROCHESTER - Rochester NY
International Classification:
C12N 15/113, A61K 38/17, A61K 31/7088, C07K 16/28, C07K 14/71, A61K 39/395, A61K 45/06
US Classification:
4241721, 514 81, 514 44 A
Abstract:
The present invention is directed to methods of treating an inflammatory condition in a patient. This method includes providing a therapeutic agent that is a vascular endothelial growth factor receptor-3 (VEGFR-3) agonist or a nucleic acid molecule encoding a VEGFR-3 agonist. The present invention is further directed to pharmaceutical compositions and therapeutic systems for treating an inflammatory condition.