BRADLEY E BERNSTEIN, M.D.
Medical Practice at Larch Rd, Cambridge, MA
License number
Massachusetts 216499
Category
Medical Practice
Type
Clinical Pathology/Laboratory Medicine
Address
Address
146 Larch Rd, Cambridge, MA 02138
Phone
(617) 256-5520
Personal information
See more information about BRADLEY E BERNSTEIN at radaris.comName
Address
Phone
146 Larch Rd, Cambridge, MA 02138
Cambridge, MA
146 Larch Rd, Cambridge, MA 02138
146-148 Larch Rd, Cambridge, MA 02138
57 Lawton St, Brookline, MA 02446
Professional information
Agents Providing Controls And Standards For Immuno-Precipitation Assays
US Patent:
2013021, Aug 22, 2013
Filed:
Mar 29, 2013
Appl. No.:
13/853216
Inventors:
Bradley E. BERNSTEIN - Cambridge MA, US
Alon Goren - Cambridge MA, US
Alon Goren - Cambridge MA, US
Assignee:
The General Hospital Corporation d/b/a Massachusetts General Hospital - Boston MA
International Classification:
C07K 9/00, C12Q 1/68
US Classification:
435 612, 530322, 435 61
Abstract:
Control agents for immuno-precipitation assays, methods of using the control agents and kits comprising the control agents are provided.
Methods For Preparing Sequencing Libraries
US Patent:
2011018, Aug 4, 2011
Filed:
Feb 3, 2010
Appl. No.:
12/699508
Inventors:
Mazhar Adli - Malden MA, US
Bradley E. Bernstein - Cambridge MA, US
Tarjei S. Mikkelsen - Cambridge MA, US
Bradley E. Bernstein - Cambridge MA, US
Tarjei S. Mikkelsen - Cambridge MA, US
International Classification:
C12Q 1/68, C07H 21/04, C12N 9/96, C12P 19/34
US Classification:
435 612, 536 231, 435188, 536 2433, 435 912
Abstract:
Improvements in chromatin immunoprecipitation-high throughput sequencing techniques has allowed the creation of chromatin maps from limited biological sample sizes that cannot be evaluated using conventional chromatin immunoprecipitation-sequencing protocols. For example, a modified universal primer is utilized that incorporates restriction enzymes into chromatin immunoprecipitation fragments before amplification. The improved method allows the sample sizes to be several orders of magnitude less than that required for standard ChIP-Seq techniques.