DR. BRADLEY C POFF, DVM
Veterinary at Southridge Ave, Saint Paul, MN

License number

Minnesota 13588

Professional information

Redox And Photoinitiator Systems For Priming For Improved Adherence Of Gels To Substrates

US Patent:

6387977, May 14, 2002

Filed:

Jul 14, 2000

Appl. No.:

09/616256

Inventors:

Amarpreet S. Sawhney - Lexington MA
David A. Melanson - Hudson NH
Chandrashekar P. Pathak - Lexington MA
Jeffrey A. Hubbell - San Marino CA
Luis Z. Avila - Arlington MA
Mark T. Kieras - Newburyport MA
Stephen D. Goodrich - Woburn MA
Shikha P. Barman - Lowell MA
Arthur J. Coury - Boston MA
Ronald S. Rudowsky - Sudbury MA
Douglas J. K. Weaver - Bedford MA
Marc A. Levine - Fremont CA
John C. Spiridigliozzi - Dedham MA
Thomas S. Bromander - Andover MA
Dean M. Pichon - Concord MA
George Selecman - Marblehead MA
David J. Nedder - Attleboro MA
Bradley C. Poff - White Bear Lake MN
Donald L. Elbert - Pasadena CA

Assignee:

Focal, Inc. - Lexington MA
Board of Regents, The University of Texas System - Austin TX

International Classification:

C09D 400

US Classification:

522184, 522185, 424487, 602904, 523111, 523114, 523118

Abstract:

An impoved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, tissue is stained with a photoinitiator, then the polymer solution or gel having added thereto a defined amount of the same or a different photoinitiator is applied to the tissue. On exposure to light, the resulting system polymerizes at the surface, giving excellent adherence, and also forms a gel in the rest of the applied volume. Thus a gel barrier of arbitrary thickness can be applied to a surface while maintaining high adherence at the interface. This process is referred to herein as âprimingâ. The polymerizable barrier materials are highly useful for sealing tissue surfaces and junctions against leaks of fluids. In another embodiment, âprimingâ can be used to reliably adhere preformed barriers to tissue or other surfaces, or to adhere tissue surfaces to each other.

Redox And Photoinitiator Systems For Priming And Improved Adherence Of Gels To Substrates

US Patent:

6121341, Sep 19, 2000

Filed:

Oct 10, 1997

Appl. No.:

8/973077

Inventors:

Assignee:

Board of Regents, The University of Texas System - Austin TX
Focal, Inc. - Lexington MA

International Classification:

C08K 100, A61F 200

US Classification:

522 84

Abstract:

An impoved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment, tissue is stained with a photoinitiator, then the polymer solution or gel having added thereto a defined amount of the same or a different photoinitiator is applied to the tissue. On exposure to light, the resulting system polymerizes at the surface, giving excellent adherence, and also forms a gel in the rest of the applied volume. Thus a gel barrier of arbitrary thickness can be applied to a surface while maintaining high adherence at the interface. This process is referred to herein as "priming". the polymerizable barrier materials are highly useful for sealing tissue surfaces and junctions against leaks of fluids. In another embodiment, "priming" can be used to reliably adhere preformed barriers to tissue or other surfaces, or to adhere tissue surfaces to each other.

Trocar

US Patent:

5533977, Jul 9, 1996

Filed:

Mar 7, 1995

Appl. No.:

8/400460

Inventors:

Gerald L. Metcalf - Burnsville MN
Bradley C. Poff - White Bear Lake MN
John M. Barker - Ventura CA

Assignee:

Origin Medsystems, Inc. - Menlo Park CA

International Classification:

A61M 5178, A61M 2500

US Classification:

604164

Abstract:

A trocar for placement in the lumen of a cannula to facilitate inserting the cannula through tissue is disclosed. The trocar has an improved trigger/obturator assembly wherein the trigger comprises tissue cam parts each having (a) planar outer surfaces, and (b) an arcuate end portion at the distal end of the trigger including a distal edge surface that is arcuate about an axis normal to the outer surfaces. The arcuate end portions intersect at edge surfaces which are obscured by the arcuate end portions.