BO FENG
Medical Practice in Teaneck, NJ
License number
Pennsylvania MT182775
Category
Medicine
Type
Graduate Medical Trainee
Address
Address
2
Teaneck, NJ 07666
Pennsylvania
Pennsylvania
Professional information
Compositions And Methods Relating To Abca1-Mediated Cholesterol Efflux
US Patent:
2003023, Dec 25, 2003
Filed:
Apr 30, 2003
Appl. No.:
10/426415
Inventors:
Ira Tabas - New City NY, US
Bo Feng - Teaneck NJ, US
Bo Feng - Teaneck NJ, US
International Classification:
C12Q001/60
US Classification:
435/011000
Abstract:
This invention provides a method for determining whether an agent increases ABCA1-dependent cholesterol efflux from a cell. This invention also provides methods for increasing cholesterol efflux from a cell and for decreasing the amount of cholesterol in a cell. This invention further provides methods for increasing the likelihood that a cholesterol-loaded macrophage will survive and for decreasing the likelihood that a cholesterol-loaded macrophage will contribute to the progression of atherosclerosis. Finally, this invention provides a method for treating a subject afflicted with atherosclerosis, and a related article of manufacture.