BLAKE J ROESSLER, MD
Osteopathic Medicine in Ann Arbor, MI
License number
Michigan 4301047982
Category
Osteopathic Medicine
Type
Internal Medicine
License number
Michigan 4301047982
Category
Osteopathic Medicine
Type
Rheumatology
Address
Address
1500 Floor Taubman Ctr, Ann Arbor, MI 48109
Phone
(734) 647-5900
(734) 936-2047
(734) 936-2047
Personal information
See more information about BLAKE J ROESSLER at radaris.comName
Address
Phone
3175 Dolph Dr #1, Ann Arbor, MI 48103
3175 Dolph Dr, Ann Arbor, MI 48103
600 E Washington St #3, Ann Arbor, MI 48104
Ann Arbor, MI
3175 Dolph Dr, Ann Arbor, MI 48103
Professional information
Dr. Blake J Roessler, Ann Arbor MI - MD (Doctor of Medicine)
Specialties:
Rheumatology
Address:
University Of MI Medcl Ctr-RHU
1500 E Medical Center Dr, Ann Arbor 48109
(734) 647-5900 (Phone)
1500 E Medical Center Dr, Ann Arbor 48109
(734) 647-5900 (Phone)
Procedures:
Joint Drainage, Steroid Injections, Viscosupplementation With Hyaluronate
Conditions:
Adhesive Capsulitis, Antiphospholipid Syndrome (APS), Arthritis, Behçet's Disease, Calcium Pyrophosphate Dihydrate Deposition Disease (CPPD), Carpal Tunnel Syndrome, Chronic Neck Pain, Cryoglobulinemia, Dermatomyositis, Enthesopathy of Knee (incl. Bursitis of Knee), Fibromyalgia, Giant Cell Arteritis, Gout, Hammer Toe, HenochâÂÂSchönlein Purpura (HSP), Immune Thrombocytopenic Purpura (ITP), Low Back Pain, Lupus Erythematosus, Osteoarthritis, Osteoarthritis of Hand or Wrist, Osteoarthritis of Hip, Osteoarthritis of Knee, Osteoarthritis of Spine, Osteopenia, Osteoporosis, Patellofemoral Pain Syndrome or Knee Pain, Polymyalgia Rheumatica (PMR), Polymyositis, Raynaud's Disease, Reiter's Syndrome (Reactive Arthritis), Rheumatoid Arthritis, Sarcoidosis, Sjögren's Syndrome, Spondylitis, Still's Disease, Systemic Lupus Erythematosus (SLE), Systemic Sclerosis, Systemic Vasculitis, Vasculitis, Wegener's Granulomatosis
Certifications:
Internal Medicine, 1986, Rheumatology, 2002
Awards:
Healthgrades Honor Roll
Languages:
English
Hospitals:
University Of MI Medcl Ctr-RHU
1500 E Medical Center Dr, Ann Arbor 48109
University of Michigan Health System
1500 East Medical Center Dr SPC 5474, Ann Arbor 48109
1500 E Medical Center Dr, Ann Arbor 48109
University of Michigan Health System
1500 East Medical Center Dr SPC 5474, Ann Arbor 48109
Education:
Medical School
University Of Cincinnati College Of Medicine
Graduated: 1983
University Mich Med Center
Graduated: 1984
Graduated: 1986
Stanford University
University Of Cincinnati College Of Medicine
Graduated: 1983
University Mich Med Center
Graduated: 1984
Graduated: 1986
Stanford University
Method And Apparatus For Evaluating Connective Tissue Conditions
US Patent:
7729749, Jun 1, 2010
Filed:
Sep 1, 2005
Appl. No.:
11/217755
Inventors:
Blake J. Roessler - Ann Arbor MI, US
Michael D. Morris - Ann Arbor MI, US
Karen A. Dehring - Ypsilanti MI, US
Michael D. Morris - Ann Arbor MI, US
Karen A. Dehring - Ypsilanti MI, US
Assignee:
The Regents of the University of Michigan - Ann Arbor MI
International Classification:
A61B 6/00
US Classification:
600476, 356301
Abstract:
Methods and apparatus are provided for evaluating a connective tissue condition of a patient (e. g. , a disease, a risk of developing a disease, a risk of developing a fracture, etc. ). For example, an indicator associated with the connective tissue condition may be generated. First, tissue at a first location of the body of the patient is irradiated using a light source. The tissue may be irradiated in vivo through the skin or via an incision, for example. Alternatively, a biopsy of the tissue may be irradiated. Then, spectral content information for light scattered, reflected, or transmitted by the irradiated tissue is determined. The spectral content information may be used, at least in part, to generate an indicator associated with a condition of connective tissue at a second location of the body of the patient, the second location remote from the first location. The indicator may, for example, assist a physician in diagnosing or ruling out the connective tissue condition.
Adenoviral-Mediated Gene Transfer To Synovial Cells In Vivo
US Patent:
5747072, May 5, 1998
Filed:
Apr 14, 1995
Appl. No.:
8/422655
Inventors:
Beverly L. Davidson - Howell MI
Blake J. Roessler - Ann Arbor MI
Blake J. Roessler - Ann Arbor MI
Assignee:
University of Michigan - Ann Arbor MI
International Classification:
A61K 4800, C12N 1509, C12N 1563
US Classification:
424 932
Abstract:
This invention provides recombinant adenoviral vectors having an expression control sequence operatively linked to a gene that encodes an anti-inflammatory polypeptide or that produces on transcription an anti-inflammatory ribozyme or antisense RNA molecule. This invention also provides methods of transferring a gene to a synovial cell by transducing the synovial cell in vivo, with a recombinant adenoviral vector. This invention also provides methods of treating an inflammatory condition in the joint of a subject comprising administering to the joint a therapeutically effective amount of a recombinant adenoviral vector having an expression control sequence operatively linked to a gene that encodes an anti-inflammatory polypeptide or that produces on transcription an anti-inflammatory ribozyme or antisense RNA molecule.
Method And Apparatus For Evaluating Connective Tissue Conditions
US Patent:
2005011, Jun 2, 2005
Filed:
Sep 17, 2004
Appl. No.:
10/944518
Inventors:
Blake Roessler - Ann Arbor MI, US
Michael Morris - Ann Arbor MI, US
Steven Goldstein - Ann Arbor MI, US
Abigail Smukler - Ann Arbor MI, US
Nicole Crane - Ypsilanti MI, US
Barbara McCreadie - Ann Arbor MI, US
Tso-Ching Chen - Whitmore Lake MI, US
Michael Morris - Ann Arbor MI, US
Steven Goldstein - Ann Arbor MI, US
Abigail Smukler - Ann Arbor MI, US
Nicole Crane - Ypsilanti MI, US
Barbara McCreadie - Ann Arbor MI, US
Tso-Ching Chen - Whitmore Lake MI, US
Assignee:
UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61B010/00
US Classification:
600562000
Abstract:
In a method for evaluating a connective tissue condition of a patient, an indicator of the supporting tissue condition may be generated. A portion of connective tissue of the patient is irradiated using a light source. The connective tissue may be irradiated in vivo through the skin or via an incision, for example. Alternatively, a biopsy of the connective tissue may be irradiated. Then, spectral content information for light scattered, reflected, or transmitted by the connective tissue is determined. The spectral content information is used, at least in part, to generate the indicator. The indicator may assist a physician in diagnosing or ruling out the connective tissue condition, determining a risk of developing a disease, monitoring the progression of a disease, monitoring a response to treatment, etc.
Method And Apparatus For Evaluating Ocular Tissue Conditions
US Patent:
2010023, Sep 16, 2010
Filed:
May 24, 2010
Appl. No.:
12/785933
Inventors:
Blake J. Roessler - Ann Arbor MI, US
Michael D. Morris - Ann Arbor MI, US
Karen A. Dehring - Ypsilanti MI, US
Michael D. Morris - Ann Arbor MI, US
Karen A. Dehring - Ypsilanti MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
A61B 6/00, G01J 3/44
US Classification:
600476, 356301
Abstract:
Methods and apparatus are provided for evaluating an ocular tissue condition of a patient (e.g., a disease, a risk of developing a disease, etc.). For example, an indicator associated with the ocular tissue condition may be generated. A portion of ocular tissue of the patient is irradiated using a light source. Light from the portion of the ocular tissue is received. Raman spectra information associated with the received light is determined. An indicator of an ocular tissue condition is generated based at least on the Raman spectra information. The indicator may, for example, assist a physician in diagnosing or ruling out the ocular tissue condition.
Methods And Compositions Of Gene Delivery Agents For Systemic And Local Therapy
US Patent:
2008002, Jan 31, 2008
Filed:
Dec 8, 2006
Appl. No.:
11/608370
Inventors:
John Hilfinger - Ann Arbor MI, US
Phillip Kish - Ann Arbor MI, US
Blake Roessler - Ann Arbor MI, US
Phillip Kish - Ann Arbor MI, US
Blake Roessler - Ann Arbor MI, US
International Classification:
C07K 14/00, A61K 31/19, A61K 31/195, A61K 31/351, A61K 31/397, A61K 31/40, A61K 31/401, A61K 31/403, A61K 31/405, A61K 31/407, A61K 31/415, A61K 31/4164, A61K 31/43, A61K 31/4355, A61K 31/44, A61K 31/47, A61K 31/485, A61K 31/4965, A61K 31/497, A61K 31/519, A61K 31/535, A61K 31/545, A61K 31/55, A61K 31/60, A61K 31/704, A61K 33/06, A61K 33/08, A61K 33/26, A61K 38/00, A61P 43/00
US Classification:
424648000, 424687000, 424690000, 424692000, 514159000, 514165000, 514002000, 514210170, 514212070, 514224200, 514230200, 514249000, 514252170, 514253040, 514253080, 514254040, 514255060, 514026000, 514262100, 514282000, 514283000, 514300000, 514314000, 514361000, 514368000, 514383000, 514389000, 514394000, 514409000, 514411000, 514412000, 514413000, 514415000, 514423000, 514459000, 514561000, 514568000, 514789000, 530324000
Abstract:
A method is provided for the delivery of a therapeutic to epithelial cells through the use of a bile acid conjugated to a peptide, the peptide being ionically charged at physiological pH. The complex is well suited for oral and other forms of therapeutic administration of therapeutic drugs known in the art in order to exact systemic and/or localized effect. Intestinal epithelial cells, as well as non-epithelial cells within the gastrointestinal tract and other target cells receive with greater efficiency a charged therapeutic when delivered with an oppositely charged bile acid conjugate (BAC) through oral administration, direct injection, or infusive administrations, thereby increasing bioavailability.
Method And Apparatus For Measuring Cartilage Condition Biomarkers
US Patent:
2007008, Apr 12, 2007
Filed:
Sep 14, 2006
Appl. No.:
11/521295
Inventors:
Michael Morris - Ann Arbor MI, US
Blake Roessler - Ann Arbor MI, US
Gurjit Mandair - Ann Arbor MI, US
Karen Dehring - Ypsilanti MI, US
Blake Roessler - Ann Arbor MI, US
Gurjit Mandair - Ann Arbor MI, US
Karen Dehring - Ypsilanti MI, US
Assignee:
THE REGENTS OF THE UNIVERSITY OF MICHIGAN - Ann Arbor MI
International Classification:
G01N 21/62
US Classification:
436171000
Abstract:
In a method for measuring cartilage condition biological markers, a surface-enhanced Raman spectroscopy (SERS) substrate is irradiated using a light source, the SERS substrate having deposited thereon a biological sample. Light scattered by the SERS substrate is received, and spectral content information associated with the received light is determined. A level of a cartilage condition biological marker in the biological sample is determined based on the spectral content information.
Delivery Systems Comprising Biocompatible And Bioerodable Membranes
US Patent:
2004012, Jun 24, 2004
Filed:
May 30, 2001
Appl. No.:
09/867924
Inventors:
Blake Roessler - Ann Arbor MI, US
James Baker - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US
James Baker - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US
International Classification:
C08G063/91, C08G063/48, A61F002/00
US Classification:
424/426000, 525/054100
Abstract:
The present invention relates to novel compositions and methods for delivering substances to target tissues and cells by contacting the targets with delivery systems associated with membranes (e.g., biocompatible or bioerodable membranes). More particularly, the present invention is directed to dendrimer-based methods and compositions for use in disease therapies, wound healing, and generally, improved gene transfection and compound delivery to target cells and tissues in vitro and in vivo.
Ballistic Transfection With Dendrimers
US Patent:
2004010, Jun 10, 2004
Filed:
May 8, 2003
Appl. No.:
10/431682
Inventors:
James Baker - Ann Arbor MI, US
Blake Roessler - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US
Blake Roessler - Ann Arbor MI, US
Anna Bielinska - Ypsilanti MI, US
International Classification:
A61K048/00, C08G063/48, C08G063/91
US Classification:
424/078290, 525/054200
Abstract:
The present invention relates to compositions and methods involving biocompatible dendrimers. In particular, the present invention provides dendrimeric copolymers with poly(propyleneimine) (POPAM) interiors and poly(amidoamine) (PAMAM) exteriors for use in transfection and imaging applications.
Nanoemulsion Formulations
US Patent:
2002015, Oct 24, 2002
Filed:
May 30, 2001
Appl. No.:
09/867930
Inventors:
Blake Roessler - Ann Arbor MI, US
James Baker - Ann Arbor MI, US
Norman Weiner - Ann Arbor MI, US
Ramachandran Chandrasekharan - Ypsilanti MI, US
Huai Wu - Lake Bluff IL, US
James Baker - Ann Arbor MI, US
Norman Weiner - Ann Arbor MI, US
Ramachandran Chandrasekharan - Ypsilanti MI, US
Huai Wu - Lake Bluff IL, US
Assignee:
The Regents of the University of the Michigan - Ann Arbor MI
International Classification:
A61K007/075
US Classification:
424/070210
Abstract:
The present invention relates to nanoemulsion formulations and methods for delivering biological agents to cells, and in particular nanoemulsion formulations for parenteral and non-parenteral delivery of biological agents to a subject. The nanoemulsion formulations of the present invention may be employed to permit the permeation of biological agents into the skin of subject or to increase the rate of permeation. Biological agents may be delivered by the nanoemulsion formulations of the present invention for diagnostic or therapeutic purposes.