BARRON W TENNEY
Broker in Haverhill, MA

8574615, Nov 5, 2013

May 25, 2010

12/787209

Barron Tenney - Haverhill MA, US
Yixin Xu - Newton MA, US
Michael N. Helmus - Worcester MA, US

Boston Scientific Scimed, Inc. - Maple Grove MN

A61F 2/02

424423

According to an aspect of the present invention, implantable or insertable medical devices are provided which contain (a) one or more depressions that contain at least one therapeutic agent, and (b) a nanoporous coating, disposed over the therapeutic-agent-containing depressions, which regulate transport of species between the therapeutic-agent-containing depressions and the exterior of the device. The implantable or insertable devices are configured to preform a role beyond mere drug delivery, for example, providing mechanical and/or electrical functions within the body, among other functions. An advantage of the present invention is that medical devices may be provided, which release therapeutic agents in quantities far exceeding the void volume within the nanoporous coating, while at the same time providing functionality that extends beyond drug delivery. Such release may further approach or achieve a zero order kinetic drug release profile.

2008008, Apr 10, 2008

Oct 10, 2006

11/545439

Barron Tenney - Haverhill MA, US
Michael N. Helmus - Worcester MA, US
Yixin Xu - Newton MA, US

A61K 9/22

6048921

According to an aspect of the invention, implantable or insertable medical devices are provided which contain the following: (a) one or more porous regions comprising pores and (b) one or more therapeutic agents which are (i) contained within the porous region, (ii) disposed beneath the porous region, or (iii) both. Moreover, the porous regions are capable of undergoing a change in configuration, such that the pores undergo a change in configuration, upon subjecting the porous regions to activating stimuli.

2008020, Aug 28, 2008

Feb 25, 2008

12/072141

Michael N. Helmus - Worcester MA, US
Barron Tenney - Haverhill MA, US
Yixin Xu - Newton MA, US
Kevin M. Alves - New Bedford MA, US
Frederick H. Strickler - Natick MA, US
Kathleen M. Miller - Shrewsbury MA, US
Mark Boden - Harrisville RI, US

Boston Scientific Scimed, Inc. - Maple Grove MN

A61F 2/06

623 144, 623 113, 623 115, 623 139

According to an aspect of the present invention, long term medical articles are provided which include the following: (a) first and second body contacting (e.g., tissue and/or body-fluid contacting) porous polymeric layers; (b) a polymeric barrier layer disposed between the first and second porous polymer layers; and (c) a reinforcement element. According to another aspect of the present invention, tubular medical articles for long term implantation are provided, which comprise: (a) a reinforcement element; (b) a blood contacting porous polymeric layer having a surface energy ranging between 20 and 30 dynes/cm disposed over an inner surface of the reinforcement element; and (c) an additional porous polymeric layer formed over an outer surface of the reinforcement element.

7737060, Jun 15, 2010

Mar 31, 2006

11/395964

Frederick H. Strickler - Natick MA, US
Barron Tenney - Haverhill MA, US

Boston Scientific Scimed, Inc. - Maple Grove MN

B32B 5/02, B32B 27/12, B32B 15/14, A61F 2/01, A61F 2/02, A61F 2/82, A61F 13/00

442361, 442123, 442199, 442200, 442201, 442202, 442228, 442229, 442238, 442362, 442363, 442364, 442365, 442376, 442377, 602 44, 602 45, 6048911, 604 9301, 606228, 606230, 606908, 606910

According to an aspect of the present invention, medical devices are provided that contain at least one multi-component polymeric fiber. The multi-component polymeric fiber further contains at least two components of differing composition.

8221783, Jul 17, 2012

Sep 10, 2008

12/207839

Michael N. Helmus - Worcester MA, US
Yixin Xu - Newton MA, US
Barron W. Tenney - Haverhill MA, US
Paul L. Valint - Pittsford NY, US
Shrirang V. Ranade - Arlington MA, US

Boston Scientific Scimed, Inc. - Maple Grove MN

C08B 37/08, C08L 71/02, A61K 47/36, A61K 47/42, A61K 9/70, A61K 9/00, A61K 31/337, A61K 31/436, A61K 47/38, A61F 2/02, C07K 14/78, C08F 210/00, C08G 63/06, C08G 67/00, C08G 73/00, C08G 73/10

424434, 424422, 526348, 526258, 528367, 536 56, 536 30, 536 58, 536 3, 536 20, 525408, 530354, 5147723, 5147724, 5147726, 514291, 514279, 514449, 514777, 514779, 514781, 514773, 514774, 623 1111, 623 116, 623 146, 623 142, 623 136

Described herein are implantable medical devices comprising a biocompatible polymer comprising a triggerable bioadhesive property that allows the device to adhere to body tissue. The triggerable bioadhesive property of the polymer can be triggered or activated by exposure to a stimulus. Also, the present invention pertains to methods of making an implantable medical device comprising a biocompatible polymer comprising a triggerable bioadhesive property that allows the device to adhere to body tissue.

2009015, Jun 18, 2009

Dec 12, 2007

12/001656

Frederick H. Strickler - Natick MA, US
Barron Tenney - Haverhill MA, US
Mark Boden - Harrisville RI, US

Boston Scientific Scimed, Inc. - Maple Grove MN

B28B 1/14, C08F 6/00, C08F 20/10, C08F 236/06, C08F 10/02, C08F 12/08

526328, 528502 R, 526340, 5263482, 264299

In accordance with an aspect of the invention, methods of forming medical articles are provided, which comprise (a) preparing a melt phase that comprises a molten polymer and a supercritical fluid, (b) forming a polymeric region from the melt phase, and (c) cooling the polymeric region. In certain embodiments, the supercritical fluid is formed from chemical species (e.g., CO, propane, etc.) that are gases at room temperature (25° C.) and atmospheric pressure (1 atm). According to another aspect of the present invention, medical articles are provided which comprise melt-processed polymeric materials. The polymeric materials have a composition that cannot be melt processed without the use of melt-viscosity reducing additives due to thermal degradation, and yet the polymeric material does not contain such additives.

2005020, Sep 22, 2005

Mar 16, 2004

10/801228

Michael Helmus - Worcester MA, US
Barron Tenney - Haverhill MA, US

A61F002/06, A61K009/70

424443000, 442123000, 623001110

According to an aspect of the present invention, a fiber comprising a styrene-isobutylene copolymer is formed by via a dry spinning process. Specific examples of copolymers for the practice of the present invention include copolymers comprising a polyisobutylene block and a polystyrene block, for instance, a polystyrene-polyisobutylene-polystyrene triblock copolymer. Other aspects of the present invention relate to medical articles which comprise the above dry spun fibers. Specific examples include medical articles comprising a woven region formed from the dry spun fibers, and medical articles comprising a non-woven region formed from the dry spun fibers.

2009010, Apr 23, 2009

Sep 19, 2008

12/234463

Aiden Flanagan - Galway, IE
Mark Boden - Harrisville RI, US
Frederick H. Strickler - Natick MA, US
Barron W. Tenney - Haverhill MA, US

BOSTON SCIENTIFIC SCIMED, INC. - Maple Grove MA

A61F 2/82, A61K 31/335, A61K 31/4353, A61K 38/18

424423, 514449, 514291, 514 12

A medical device comprising: (a) a substrate having first and second surfaces, (b) a therapeutic-agent-eluting polymeric layer disposed over the first substrate surface and (c) a textured polymeric layer that is textured to promote cell attachment, cell growth, or both, disposed over the second surface.

2009006, Mar 12, 2009

Jul 24, 2008

12/179115

Paul DiCarlo - Middleboro MA, US
Barron W. Tenney - Haverhill MA, US
Yixin Xu - Newton Lower Falls MA, US
Michael N. Helmus - Worcester MA, US

BOSTON SCIENTIFIC SCIMED, INC. - Maple Grove MN

A61K 9/14, B32B 15/02, B32B 27/02

424489, 428401, 428375, 428379, 428377, 428376

Embolic particles, embolic particle chains, and methods for making embolic particles and embolic particle chains are described.