Inventors:
Mohammed Safadi - Nazareth, IL
Maya Barder - Haifa, IL
Yechiel Golander - Haifa, IL
Avraham Yacobi - Englewood NJ, US
Daniel Moros - Larchmont NY, US
Barrie Levitt - Mamaroneck NY, US
Michael Friedman - Jerusalem, IL
Assignee:
TARO PHARMACEUTICAL INDUCTRIES LTD.
International Classification:
A61K031/19
Abstract:
The invention provides a process for preparing a non-hygroscopic, highly stable, oral pharmaceutical composition of a salt of valproic acid. The pharmaceutical composition is prepared by blending ingredients including a hygroscopic salt of valproic acid, carbomer, and a non-hygroscopic additive such as dibasic calcium phosphate. Such a composition forms non-hygroscopic, highly moisture stable solid dosage form.