Barbara Jeanne Corn
Nursing at 2 St, Shade, OH
License number
Colorado 77852
Issued Date
Feb 1, 1984
Renew Date
Sep 30, 1989
Expiration Date
Sep 30, 1989
Type
Registered Nurse
Address
Address
2
18 2Nd St, Shade, OH 45701
Shade, OH
Shade, OH
Professional information
Gene Transfer Using Transformed, Neodetermined, Embryonic Cells
US Patent:
5032407, Jul 16, 1991
Filed:
Jan 16, 1987
Appl. No.:
7/004077
Inventors:
Thomas E. Wagner - Athens OH
Michael A. Reed - Athens OH
Barbara J. Corn - Athens OH
Michael A. Reed - Athens OH
Barbara J. Corn - Athens OH
Assignee:
Ohio University Edison Animal Biotechnology Center - Athens OH
International Classification:
A61K 3500, C12N 1500, C12N 500
US Classification:
424520
Abstract:
This invention is directed to a method for the preparation of carrier cells capable of delivering exogenous genetic material to a particular tissue of the body by means of embryonic cells competent to develop into that tissue, and essentially only that tissue, said cells bearing the exogenous genetic material. The preferred carrier cells are mesodermal cells of the yolk sac or embryonic forebrain or midbrain cells, and the desired genetic material is preferably introduced into the cells by in vitro transformation with an amphotrophic retroviral vector.