BARBARA J MASON
Psychologist in Rancho Santa Fe, CA
License number
Florida 4630
Issued Date
Dec 16, 1991
Effective Date
Jun 2, 2010
Expiration Date
May 31, 2010
Category
Health Care
Type
Psychologist
Address
Address
2
PO Box 3589, Rancho Santa Fe, CA 92067
10550 N Torrey Pines Rd, La Jolla, CA 92037
10550 N Torrey Pines Rd, La Jolla, CA 92037
Phone
(858) 759-5309
Professional information
Mpzp: A Small Molecule Corticotropin-Releasing Factor Type 1 Receptor (Crf1) Antogonist
US Patent:
2010024, Sep 30, 2010
Filed:
Sep 12, 2008
Appl. No.:
12/677770
Inventors:
George F. Koob - Rancho Santa Fe CA, US
Eric P. Zorrilla - San Diego CA, US
Barbara Mason - Rancho Santa Fe CA, US
Kim Janda - La Jolla CA, US
Peter Wirsching - Del Mar CA, US
Eric P. Zorrilla - San Diego CA, US
Barbara Mason - Rancho Santa Fe CA, US
Kim Janda - La Jolla CA, US
Peter Wirsching - Del Mar CA, US
International Classification:
A61K 31/53, A61K 31/519
US Classification:
514246, 51426411, 5142593
Abstract:
A method for treating or preventing a host mammal that exhibits aversive signs and symptoms present during protracted abstinence or extended discontinuation syndromes as seen after cessation of compulsive activity, behaviors, or substance use is disclosed. That method comprises administering to a host mammal in need a pharmaceutical composition containing an aversive sign and symptom lessening amount a compound of Formula I or a pharmaceutically acceptable salt thereof dissolved or dispersed in a physiologically acceptable diluent, and repeating the administration as needed,wherein W, X, Y and Z, Rand Ar are defined within. Data are provided in rats as host mammals using behavioral models dependent on the CRFsystem: defensive burying, alcohol dependence, cocaine dependence and nicotine dependence. A contemplated method also is useful for inhibiting relapse of such a behavior. A contemplated method also is useful for treating substance-related or substance-induced psychiatric disorders that include aversive signs and symptoms.
Methods For Treating Substance Dependence
US Patent:
2010028, Nov 4, 2010
Filed:
Apr 23, 2010
Appl. No.:
12/799376
Inventors:
Barbara J. Mason - Rancho Santa Fe CA, US
George F. Koob - Rancho Santa Fe CA, US
George F. Koob - Rancho Santa Fe CA, US
Assignee:
The Scripps Research Institute - La Jolla CA
International Classification:
A61K 31/197, A61K 31/195, A61P 25/30, A61P 25/32
US Classification:
514561
Abstract:
The present invention provides methods for treating alcohol dependence and preventing relapse in subjects in protracted alcohol abstinence. Also provided are methods for treating subjects suffering from cannabis dependence. Typically, these methods entail administering to the subjects in need of treatment a therapeutically effective amount of gabapentin, an analog of gabapentin, or pharmaceutically acceptable salt thereof.