Inventors:
Barbara A. Green - Edison NJ, US
David J. Milora - Blue Bell PA, US
International Classification:
A61K 33/40, A61K 31/34, A61K 31/385, A61K 33/04, A61K 47/12, A61P 17/00, A61K 35/04, A61K 33/22, A61K 33/32
US Classification:
424616, 424640, 424660, 424667, 424703, 4247251, 514 18, 514356, 514440, 514460, 514714, 514785
Abstract:
Embodiments relate generally to topical compositions useful for treating or preventing a variety of cosmetic conditions and dermatological disorders, where the composition comprises an oxidative pharmaceutical drug and an antioxidant polyhydroxy acid or polyhydroxy lactone. The polyhydroxy acid or polyhydroxy lactone improves the cutaneous effects of the drug. The embodiments further relate to the treatment of a variety of cosmetic conditions and dermatological disorders comprising administering to a subject an effective amount of the composition and to methods of making the compositions.