Inventors:
The Board of Regents of the University of Texas System - , US
Kejin ZHOU - Dallas TX, US
Baran SUMER - Dallas TX, US
International Classification:
A61K 49/00, G01N 21/64
Abstract:
The present invention relates to pH-tunable, highly activatable multicolored fluorescent nanoplatforms and methods of using the nanoplatforms in a variety of applications including, but not limited to, investigating fundamental cell physiological processes such as pH regulation in endocytic vesicles, endosome/lysosome maturation, and effect of pH on receptor cycling and trafficking of subcellular organelles.