Inventors:
George C. Kramer - Davis CA
Azad Sheikh - Elk Grove CA
Robert A. Gunther - Davis CA
Assignee:
Regents of the University of California - Oakland CA
International Classification:
A61K 3314, A61K 3700, A61K 3170, A61K 31195
Abstract:
The invention provides a physiologically acceptable solution for treating circulatory shock in mammals which is hyperosmotic as compared to blood plasma. The solution contains a reabsorbable solute and sodium salt in a concentration having an osmolarity in excess of about 1000 mOsms. The physiologically acceptable solution can be easily administered by rapid infusion of 4-6 ml/kg body weight and results in rapid normalization of circulatory function.