Inventors:
Jayanth Panyam - Novi MI, US
Yogesh Patil - Troy MI, US
Ayman Khdair - Dearborn MI, US
Assignee:
WAYNE STATE UNIVERSITY - Detroit MI
International Classification:
A61K 31/337, A61K 47/34, A61K 47/48, A61P 35/00, A61K 51/04, A61K 31/567, A61K 38/02, A61K 31/4985, A61K 38/54, A61K 49/10
US Classification:
424 165, 5147723, 5147727, 514449, 514178, 514 2, 514249, 424 943, 424 93
Abstract:
Provided are compositions of nanoparticles, PEG and targeting moieties. The compositions are useful in treating tumors, imaging the particles in tissues, and in targeting therapeutic agents to specific tissues and locations in a patient. Also provided are methods of preparing and methods of using the compositions.