Inventors:
Inderjit Singh - Mount Pleasant SC, US
Avtar Singh - Mount Pleasant SC, US
International Classification:
A61K 31/7028, A61K 31/445, A61K 31/5375, A61K 31/4015, A61K 31/40, A61K 31/4025, A61P 25/00
US Classification:
514 25, 514315, 5142378, 514424, 514428, 514422
Abstract:
The present invention relates generally to the fields of molecular biology. More particularly, it concerns materials and methods for the treatment of nitric oxide and cytokind mediated disorders. In a preferred embodiment, PDMP may be used to inhibit the expression of iNOS and pro-inflammatory cytokines such as TNFα and IL1β.