Inventors:
Abel Ennio Moreyra - Piscataway NJ, US
Ashraf M. Koraym - East Brunswick NJ, US
Alan Chaney Wilson - North Brunswick NJ, US
Owen Rickford Carryl - Mason OH, US
International Classification:
A61K 36/68, A61K 31/215, A61P 3/00, A61K 31/702, A61K 36/899, A61K 31/366, A61K 31/40
US Classification:
424738, 514460, 514510, 514423, 514 54, 424750
Abstract:
Disclosed herein are methods of treating a condition associated with elevated cholesterol levels are provided, comprising administering to a mammal in need of such treatment a safe and effective amount of a cholesterol biosynthesis inhibitor and a soluble fiber. Further disclosed herein are kits comprising a first composition comprising a cholesterol biosynthesis inhibitor selected from the group consisting of HMG CoA reductase inhibitors, HMG CoA synthase inhibitors, and mixtures thereof; and a second composition comprising a soluble fiber. Even further described are compositions comprising a cholesterol biosynthesis inhibitor selected from the group consisting of HMG CoA reductase inhibitors, HMG CoA synthase inhibitors, and mixtures thereof; and a soluble fiber.