ASHLEY M DAVIS
Nursing at Scranton St, Denver, CO
License number
Colorado 756692
Issued Date
Jul 25, 2013
Renew Date
Feb 1, 2016
Expiration Date
Jan 31, 2017
Type
Certified Nurse Aide
Address
Address
3116 Scranton St, Denver, CO 80011
Professional information
Ashley Davis - Denver, CO
Work:
Virginia Women's Center
Medical Assistant Locke A. Taylor DVM INC - Richmond, VA
Veterinary Assistant
Medical Assistant Locke A. Taylor DVM INC - Richmond, VA
Veterinary Assistant
Education:
Virginia Commonwealth University - Richmond, VA
Bachelor's in Interdisciplinary Studies & Education
Bachelor's in Interdisciplinary Studies & Education
Ashley Davis - Aurora, CO
Work:
The Clinic
Administrative Assistant Red Envelope - San Diego, CA
Sales Associate
Administrative Assistant Red Envelope - San Diego, CA
Sales Associate
Education:
Kearny High School - San Diego, CA
Diploma in General
Diploma in General
Lyophilized Tubulins
US Patent:
6750330, Jun 15, 2004
Filed:
May 13, 1999
Appl. No.:
09/310981
Inventors:
Ashley Davis - Denver CO 80206
Kim Middleton - Denver CO 80206
Kim Middleton - Denver CO 80206
International Classification:
C07K 1447
US Classification:
530418, 530350, 530412
Abstract:
Lyophilized active tubulin and numerous uses of lyophilized active tubulin such as diagnostic, therapeutic, drug discovery, and research applications are provided. The process of making the lyophilized active tubulin is also described.
Ashley S Davis, Northglenn CO
Specialties:
Psychotherapist
Address:
11285 Highline Dr, Northglenn, CO 80233
Anti-S-Phase Tubulin Ligands
US Patent:
7259278, Aug 21, 2007
Filed:
Nov 29, 2000
Appl. No.:
09/725030
Inventors:
Ashley Stuart Davis - Denver CO, US
Kim Maria Middleton - Denver CO, US
Jain Dong Jiang - New York NY, US
J. George Bekesi - New York NY, US
Kim Maria Middleton - Denver CO, US
Jain Dong Jiang - New York NY, US
J. George Bekesi - New York NY, US
Assignee:
Cytoskeleton Inc. - Denver CO
International Classification:
C07C 237/28
US Classification:
564161, 560 8, 562405
Abstract:
It is presently accepted that the mechanism of action for all anti-tumor tubulin ligands involves the perturbation of microtubule dynamics during the G2/M phase of cell division and subsequent entry into apoptosis (1). In this invention, we report a novel tubulin ligands which have a unique mechanism of action. These compounds, halogenated derivatives of acetamido benzoyl ethyl ester (HAABE), arrest cancer cells in S-phase and cause cell death by a combination of apoptosis (DNA ladder) and necrosis (DNA degradation) type mechanisms. Normal cells are not affected at the same concentrations of compound. The ligands bind covalently to tubulin in vitro and in vivo and shows potent cancericidal activity in tissue culture assays and in animal tumor models. These compounds target early S-phase at the G1/S transition rather than the G2/M phase and mitotic arrest. Bcl-2 phosphorylation, a marker of mitotic microtubule inhibition by other tubulin ligands was dramatically altered, phosphorylation was rapid and biphasic rather than a slow linear event.
Methods For Stabilizing Proteins
US Patent:
7282571, Oct 16, 2007
Filed:
Feb 3, 2004
Appl. No.:
10/771595
Inventors:
Ashley Stuart Davis - Denver CO, US
Kim Maria Middleton - Denver CO, US
Kim Maria Middleton - Denver CO, US
Assignee:
Cytoskeleton Inc. - Denver CO
International Classification:
C07K 14/435
US Classification:
530402, 530350, 514 2, 436172
Abstract:
In basic research and drug discovery there is a need to provide protein reagents with high activity. In particular proteins that are used in assays must have a good shelf life and a consistent activity. As a system of measuring actin polymerization, pyrene labeled actin was developed in 1983 by Kouyama and Mihashi. However, prior to this disclosure, pyrene actin has been impossible to store for longer than one month because the activity would be lost due to protein denaturation and frozen pyrene actin immediately lost activity. This disclosure relates a method for stabilizing pyrene labeled actin for extended storage times and an optimal storage buffer thus creating a reproducible source of pyrene actin for various assays. Using the processes described herein, pyrene actin has been stored for greater than 3 years at 4° C. which makes it a viable product for retail.
Method For Preserving Intracellular Molecular Detail
US Patent:
2005028, Dec 29, 2005
Filed:
Oct 30, 2003
Appl. No.:
10/696023
Inventors:
Ashley Davis - Denver CO, US
Kim Middleton - Denver CO, US
Kim Middleton - Denver CO, US
International Classification:
A01N001/02
US Classification:
435002000
Abstract:
A process and composition is described that allows the operator to fix and preserve tissue culture grown cells such that their intracellular molecular detail is retained for up to four years. This enables increased reproducibility of staining for antigens and small molecule targets for use in the areas of basic research and diagnostic applications.
Detection Of Rho Proteins
US Patent:
2010024, Sep 23, 2010
Filed:
Jun 2, 2010
Appl. No.:
12/792130
Inventors:
Li Cheng - Denver CO, US
Ashley Davis - Denver CO, US
Kim Middleton - Denver CO, US
Ashley Davis - Denver CO, US
Kim Middleton - Denver CO, US
Assignee:
CYTOSKELETON, INC. - Denver CO
International Classification:
G01N 33/573, C40B 30/04
US Classification:
506 9, 435 74
Abstract:
The present invention provides methods of detecting activated Rho GTPase proteins by contacting a solid support with a sample comprising an activated Rho GTPase protein. The solid support is linked to an activated Rho GTPase binding peptide. The activated Rho GTPase protein remains associated with the solid support during the detection.
Detection Of Rho Proteins
US Patent:
7763418, Jul 27, 2010
Filed:
Jul 3, 2006
Appl. No.:
11/428415
Inventors:
Li Cheng - Denver CO, US
Ashley Davis - Denver CO, US
Kim Middleton - Denver CO, US
Ashley Davis - Denver CO, US
Kim Middleton - Denver CO, US
Assignee:
Cytoskeleton, Inc. - Denver CO
International Classification:
C12Q 1/00, G01N 33/53, G01N 33/566
US Classification:
435 4, 435 71, 436501
Abstract:
The present invention provides methods of detecting activated Rho GTPase proteins by contacting a solid support with a sample comprising an activated Rho GTPase protein. The solid support is linked to an activated Rho GTPase binding peptide. The activated Rho GTPase protein remains associated with the solid support during the detection.
Ashley Davis
Location:
Greater Denver Area
Industry:
Mental Health Care