ASHLESH K SHETH
Pharmacy in Basking Ridge, NJ

License number
New Jersey 28RI02594500
Issued Date
Jan 14, 1998
Expiration Date
Apr 30, 2019
Category
Pharmacy
Type
Pharmacist
Address
Address
Basking Ridge, NJ

Professional information

Ashlesh Sheth Photo 1

Pharmaceutical Formulations Of An Hcv Protease Inhibitor In A Solid Molecular Dispersion

US Patent:
2011020, Aug 25, 2011
Filed:
Aug 7, 2009
Appl. No.:
13/057339
Inventors:
Ashlesh Sheth - Basking Ridge NJ, US
Chengjiu Hu - Morris Plains NJ, US
Baohua Yue - Ballwin MO, US
Marcelo Osvaldo Omelczuk - Austin TX, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 38/06, A61P 31/14, A61P 1/16
US Classification:
514 43, 514 219
Abstract:
The present invention provides pharmaceutical formulations of an HCV protease inhibitor in a solid dispersion with an excipient which provided advantageous pharmacokinetic properties for inhibiting or treating HCV infection. In preferred embodiments, the excipient is at least one polymer. The present invention also provides processes for manufacturing such formulations as well as uses of said composition for the manufacture of a medicament for treating or ameliorating one or more symptoms of HCV or disorders associated with HCV in a subject in need thereof using said formulations.