Inventors:
Ashlesh Sheth - Basking Ridge NJ, US
Chengjiu Hu - Morris Plains NJ, US
Baohua Yue - Ballwin MO, US
Marcelo Osvaldo Omelczuk - Austin TX, US
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 38/06, A61P 31/14, A61P 1/16
Abstract:
The present invention provides pharmaceutical formulations of an HCV protease inhibitor in a solid dispersion with an excipient which provided advantageous pharmacokinetic properties for inhibiting or treating HCV infection. In preferred embodiments, the excipient is at least one polymer. The present invention also provides processes for manufacturing such formulations as well as uses of said composition for the manufacture of a medicament for treating or ameliorating one or more symptoms of HCV or disorders associated with HCV in a subject in need thereof using said formulations.