Inventors:
Nareen Abboud - New Rochelle NY, US
Arturo Casadevall - New Rochelle NY, US
Assignee:
Albert Einstein College of Medicine of Yeshiva University - Bronx NY
International Classification:
A61K 39/07, A61K 39/02, A61K 39/00, A61K 38/00
US Classification:
4242461, 4241901, 4242341, 4241841, 4241921, 4242361, 514 11, 530300, 530825
Abstract:
The present invention provides a purified peptide comprising at least one of the sequences LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a vaccine, a method to protect or treat an animal from anthrax toxin, a method of making a vaccine and the use of the peptide. The present invention also provides a monoclonal antibody that specifically binds to a peptide sequence comprising at least one of the following peptide sequences: LKQKSSNSRKKRSTS (SEQ ID NO:1), or VKNKRTFLSPWISNI (SEQ ID NO:2) as well as a method to protect or treat an animal from anthrax toxin, a method of making a vaccine, a pharmaceutical composition, a method of making a pharmaceutical composition, and the use of the monoclonal antibody.