Inventors:
Richard O. Snyder - Oakland CA, US
Lawrence K. Cohen - Oakland CA, US
Mark A. Kay - Seattle WA, US
Olivier Danos - Fontainebleau, FR
Arthur R. Thompson - Seattle WA, US
Assignee:
The University of Washington - Seattle WA
Cell Genesys, Inc. - Foster City CA
International Classification:
A61K048/00, C12N015/864
US Classification:
424 932, 514 44, 435455, 435456, 4353201
Abstract:
The instant invention provides methods of expressing polynucleotides in the cells of the liver comprising administering viral particles comprising a recombinant AAV vector into a mammal, preferably a human.