Inventors:
Charles A. Lawson - Verona NJ
David J. Pinsky - Riverdale NY
Arthur Smerling - New Rochelle NY
David M. Stern - Great Neck NY
Assignee:
The Trustees of Columbia University in the City of New York - New York NY
International Classification:
C07H 19167, C07H 1920, A01N 4390
Abstract:
This invention provides a method of selectively decreasing pulmonary vascular resistance in a subject by administering endobronchially a drug chosen from among cAMP analogs, cGMP analogs, phosphodiesterase inhibitors, nitric oxide precursors, nitric oxide donors, and nitric oxide analogs.