DR. ARTHUR CHARLES COFFEY, M.D.
Radiology at Senate Blvd, Indianapolis, IN

5312436, May 17, 1994

Mar 11, 1993

8/029526

William R. Coffey - Indianapolis IN
Arthur C. Coffey - Indianapolis IN
Christopher D. Coffey - Indianapolis IN

A61B 1700

606228

A suture for use in MIS surgery and tying internally in a body cavity using graspers extending through trocars in the body wall, the suture comprising a length of suture material suitable for fastening body tissue within the body cavity, the length having opposite end portions, and gripping means attached to at least one of the end portions. The gripping means, which may be formed and shaped to facilitate engagement and movement by graspers, may be a soft, sponge-like body attached to the length end or an elongated body in the shape of a paddle attached to the length end for use by a grasper in the movement of a body organ.

5445833, Aug 29, 1995

Dec 15, 1993

8/167579

Stephen F. Badylak - West Lafayette IN
Leslie A. Geddes - West Lafayette IN
K. Donald Shelbourne - Indianapolis IN
Gary C. Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN
Methodist Hospital of Indiana, Inc. - Indianapolis IN

A61K 3538

424551

Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa, and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.

4902508, Feb 20, 1990

Jul 11, 1988

7/217299

Stephen F. Badylak - West Lafayette IN
Leslie A. Geddes - West Lafayette IN
Gary Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN

A65R 3538

424 95

This invention relates to a method for preparation of a tissue graft composition from a segment of small intestine. A tissue graft composition is described which comprises the tunica submucosa of a segment of small intestine of a warm-blooded vertebrate wherein the tunica submucosa is delaminated from the tunica muscularis and at least the luminal portion of the tunica mucosa. The tissue graft composition has been shown to have excellent mechanical characteristics, as well as non-allergenicity and non-thrombogenicity in applications as vascular autografts, vascular allografts, and vascular heterografts.

4956178, Sep 11, 1990

Nov 6, 1989

7/432591

Stephen F. Badylak - West Lafayette IN
Leslie A. Geddes - West Lafayette IN
Gary Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN

A61K 3538, A61F 206

424551

This invention relates to a method for preparation of a tissue graft composition from a segment of small intestine. A tissue graft composition is described which comprises the tunica submucosa of a segment of small intestine of a warm-blooded vertebrate wherein the tunica submucosa is deliminated from the tunica muscularis and at least the luminal portion of the tunica mucosa. The tissue graft composition has been shown to have excellent mechanical characteristics, as well as non-allergenicity and non-thrombogenicity in applications as vascular autografts, vascular allografts, and vascular heterografts.

5372821, Dec 13, 1994

Dec 15, 1993

8/168026

Stephen F. Badylak - W. Lafayette IN
Leslie A. Geddes - W. Lafayette IN
K. Donald Shelbourne - Indianapolis IN
Gary C. Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN

A61K 3538

424551

Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa and basilar mucosa tissue delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.

5573784, Nov 12, 1996

Apr 18, 1995

8/423411

Stephen F. Badylak - W. Lafayette IN
Leslie A. Geddes - W. Lafayette IN
K. Donald Shelbourne - Indianapolis IN
Gary C. Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN
Methodist Hospital of Indiana, Inc. - Indianapolis IN

A61K 3538

424551

Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa delaminated from both the tunica muscularis and at least the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.

5281422, Jan 25, 1994

Sep 24, 1991

7/764818

Stephen F. Badylak - W. Lafayette IN
Leslie A. Geddes - W. Lafayette IN
K. Donald Shelbourne - Indianapolis IN
Gary C. Lantz - Lafayette IN
Arthur C. Coffey - Indianapolis IN

Purdue Research Foundation - West Lafayette IN

A61K 3538

424551

Surgical repair of diseased or damaged endogenous connective tissue can be accomplished using a tissue graft formed from a delaminated segment of intestinal tissue. The tissue graft comprises the intestinal tunica submucosa, muscularis mucosa and stratum compactum delaminated from the tunica muscularis and the luminal portion of the tunica mucosa. The graft can be conditioned by stretching and formed as a multilayer composition for high tensile strength and resistance to tearing at its points of attachment to existing physiological structures.