DR. ARNOLD SCHWARTZ, R.PH.
Pharmacy in Cincinnati, OH

License number

Ohio 26602

Professional information

Cells Expressing Calcium Channel .Alpha.2 Subunit-Encoding Dna, Optionally With A Reporter Gene For Screening Assays

US Patent:

5618720, Apr 8, 1997

Filed:

Feb 15, 1995

Appl. No.:

8/404354

Inventors:

Steven B. Ellis - San Diego CA
Mark E. Williams - Carlsbad CA
Michael M. Harpold - San Diego CA
Arnold Schwartz - Cincinnati OH
Jean Sartor - San Diego CA
Robert Brenner - San Diego CA

Assignee:

Sibia Neurosciences, Inc. - La Jolla CA

International Classification:

C12N 1512, C12N 510, G01N 3350

US Classification:

435325

Abstract:

[DNAs] DNA molecules encoding mammalian calcium channel a. sub. 1 and a. sub. 2 subunits are provided. The [DNAs] DNA molecules are used to transform host cells which may also contain a reporter gene, the transcription of which is responsive to an ion or molecule capable of entering the cell through a calcium channel.

Arnold Schwartz, Cincinnati OH - RPH

Specialties:

Pharmacotherapy

Address:

231 Albert Sabin Way, Cincinnati 45267
(513) 558-2400 (Phone), (513) 558-1778 (Fax)

Languages:

English

Probes And Assays For Calcium Channel .Alpha..sub.2 Subunit-Encoding Nucleic Acids

US Patent:

5686241, Nov 11, 1997

Filed:

Sep 28, 1994

Appl. No.:

8/314083

Inventors:

Steven Bradley Ellis - San Diego CA
Mark E. Williams - Carlsbad CA
Michael Miller Harpold - San Diego CA
Arnold Schwartz - Cincinnati OH
Robert Brenner - Austin TX

Assignee:

Sibia Neurosciences, Inc. - La Jolla CA

International Classification:

C12N 1512, C12Q 168

US Classification:

435 56

Abstract:

Calcium channel (alpha). sub. 1 -subunit and (alpha). sub. 2 -subunit-encoding DNA, and related compositions and methods, are provided.

Method Of Administering Calcium Channel Blocking Agents

US Patent:

4504476, Mar 12, 1985

Filed:

Sep 16, 1983

Appl. No.:

6/532662

Inventors:

Arnold Schwartz - Cincinnati OH
Ingrid L. Grupp - Cincinnati OH
Gunter Grupp - Cincinnati OH
Alain de Pover - 4057 Baesel, CH

International Classification:

A61K 3133, A61K 3144

US Classification:

514211

Abstract:

A method of potentiating the effect of a dihydropyridine derivative, such as nimodipine or nifedipine, by administering d-cis-diltiazem in an amount sufficient to inhibit calcium influx but insufficient to cause substantial decrease in contractility, and administering a dihydropyridine derivative in a submicromolar amount less than the dosage normally required for pharmacological effectiveness. A calcium channel blocking composition comprises a synergistic combination of d-cis-diltiazem and a dihydropyridine derivative.

Calcium Channel Compositions And Methods

US Patent:

6013474, Jan 11, 2000

Filed:

Jun 27, 1997

Appl. No.:

8/884599

Inventors:

Steven Bradley Ellis - San Diego CA
Mark E. Williams - Carlsbad CA
Michael Miller Harpold - San Diego CA
Arnold Schwartz - Cincinnati OH
Robert Brenner - Austin TX

Assignee:

Sibia Neurosciences, Inc. - La Jolla CA

International Classification:

C12N 1512

US Classification:

435 691

Abstract:

Calcium channel (alpha). sub. 1 -subunit and (alpha). sub. 2 -subunit-encoding DNA, and related compositions and methods, are provided.

Calcium Channel .Alpha.-2 Subunit Dnas And Cells Expressing Them

US Patent:

5407820, Apr 18, 1995

Filed:

Jul 13, 1992

Appl. No.:

7/914231

Inventors:

Steven B. Ellis - San Diego CA
Mark E. Williams - Carlsbad CA
Michael M. Harpold - San Diego CA
Arnold Schwartz - Cincinnati OH
Robert Brenner - Austin TX

Assignee:

The Salk Institute Biotechnology/Industrial Associates, Inc. - La Jolla CA

International Classification:

C12N 1512, C12N 510, C12N 1589

US Classification:

4352402

Abstract:

Calcium channel. alpha. sub. 1 -subunit and. alpha. sub. 2 -subunit-encoding cDNAs, and related compositions and methods, are provided.