ARLENE GWON, MD
Medical Practice at Trafalgar, Newport Beach, CA

5627162, May 6, 1997

Jan 18, 1995

8/374360

Arlene E. Gwon - Newport Beach CA
Charles J. Hagemeier - Laguna Hills CA

A61K 3170

514 54

The present invention relates to methods to control undesired cell proliferation of remnant cells following surgery, by applying an effective amount of at least one proteoglycan-type substrate adhesion molecule (SAM) to the site of surgery. SAMs, in particular chondroitin sulfate, hyaluronic acid, and non-toxic, pharmaceutically acceptable salts thereof, alone or in a composition form, are typically used to prevent or inhibit growth of lens-related cells in a lens capsule after surgical removal of the lens, or to prevent proliferative vitreoretinopathy following retinal reattachment procedure performed with or without vitrectomy.

6291466, Sep 18, 2001

Jul 30, 1998

9/126064

Arlene Gwon - Newport Beach CA
Elizabeth WoldeMussie - Laguna Niguel CA

Allergan Sales, Inc. - Irvine CA

A67K 31505

514256

A method for increasing or decreasing parasympathetic/cholinergic/ciliary tonic contraction in order to restore the resting portion of the eye and allow normal positive and negative accommodation includes administering to a presbyopic subject an effective amount of a muscarinic agent.

6554859, Apr 29, 2003

May 3, 2000

09/565036

Alan J. Lang - Long Beach CA
Arlene Gwon - Newport Beach CA

Advanced Medical Optics, Inc. - Santa Ana CA

A61F 216

623 628, 623 632, 623 634

An intraocular lens for implantation in an eye of a patient includes a multifocal optic and a movement assembly. The optic has maximum add power which is less than the add power required for full near vision for a pseudophakic eye. The movement assembly is coupled to the optic and is adapted to cooperate with the eye of the patient to effect accommodating movement of the optic in the eye. Lens systems including two optics and two movement assemblies are also provided. The intraocular lenses and lens systems are particularly useful when implanted in the eyes of a patient after removal of the natural lenses.

2006000, Jan 5, 2006

Jun 30, 2004

10/881426

Arlene GWON - Newport Beach CA, US

A61K 31/728, A61F 2/00

424427000, 514054000

The present invention addresses the treatment of ocular conditions by the enhancement of lens regeneration. This is accomplished by the administration of a high viscosity composition including a hyaluronic acid compound. Excess high viscosity composition may be removed by focal laser photophacoablation. Additionally, a collagen product may be injected within the lens capsule to improve lens cell proliferation and differentiation, and to improve the configuration, shape and structure of regenerated lenses. Various embodiments involving the enhancement of lens regeneration are described. For example, lens regeneration may be enhanced by filling the lens capsule bag with the inventive hyaluronic acid compound; by inserting at least one collagen patch in the lens capsule; and/or by injecting a collagen-based product into the lens capsule.

5178635, Jan 12, 1993

May 4, 1992

7/878034

Arlene E. Gwon - Newport Beach CA
David Meadows - Mission Viejo CA

Allergan, Inc. - Irvine CA

A61F 214

623 4

A system for providing controlled release of an active agent in an eye includes a device with a shape thereof for enabling placement of the device under a conjunctiva of an eye and additionally preventing migration of the device in the eye after placement of the device under the conjunctiva. The device may be formed of a material permeable to the passage of an agent disposed in said device. In addition, a tracer may be incorporated in the device to enable visual indication of the amount of active agent in said device when said device is disposed under the conjunctiva. To selectively treat specific areas of the eye, an impermeable layer may be provided for preventing diffusion of the active agent from a selected area of the device.

7662180, Feb 16, 2010

Dec 5, 2002

10/314069

Marlene L. Paul - Laguna Niguel CA, US
Michael D. Lowery - Vista CA, US
Daniel Brady - San Juan Capistrano CA, US
Arlene Gwon - Newport Beach CA, US

Abbott Medical Optics Inc. - Santa Ana CA

A61F 2/16

623 656, 623 638

An accommodating IOL comprises an optic adapted to focus light toward a retina of an eye, and a movement assembly coupled to the eye to provide effective accommodating movement, preferably axial movement, of the optic. At least a portion of the movement assembly is made from a material that is less stiff and/or more resilient than the material used to make the optic. Optionally, an outer ring or support portion made at least partially from either a relatively stiff material such as the material used in the optic or a relatively resilient material such as the material used in the movement assembly is also provided.

6164282, Dec 26, 2000

Jan 27, 1999

9/238130

Arlene Gwon - Newport Beach CA
Elizabeth Woldemussie - Laguna-Niguel CA

Allergan Sales, Inc. - Irvine CA

A61B 1900

128898

A method for increasing the amount of accommodation in an eye of a mammal which eye includes an artificial intraocular lens. The method provides for administering to the mammal the amount of a muscarinic agent necessary to restore tonic accommodation.

6176878, Jan 23, 2001

Dec 17, 1998

9/213976

Arlene Gwon - Newport Beach CA
Daniel G. Brady - San Juan Capistrano CA

Allergan Sales, Inc. - Irvine CA

A61F 216

623 637

Intraocular lenses include an optic adapted to focus light toward a retina of an eye and a movement assembly coupled to the optic. The optic includes a far vision correction power for infinity reduced by a diopter power increment. The movement assembly is adapted to cooperate with the eye to move the optic bidirectionally, that is anteriorly in the eye and posteriorly in the eye, for example, from a neutral resting position in the eye, to effect positive accommodating movement of the optic and negative accommodating movement of the optic, respectively. Methods of inserting such intraocular lenses into an eye are also provided.

6129733, Oct 10, 2000

Apr 15, 1999

9/292146

Daniel G. Brady - San Juan Capistrano CA
Arlene Gwon - Newport Beach CA
Michael Collinson - Goleta CA
Claude A. Vidal - Santa Barbara CA
Alan K. Plyley - Goleta CA

Allergan Sales, Inc. - Irvine CA

A61F 900

606107

Apparatus for holding intraocular lenses and apparatus for holding intraocular lens injectors are provided which provide convenient and effective packaging systems for intraocular lenses and allow convenient and effective transfer of an intraocular lens to an injector in preparation for insertion of the intraocular lens into an eye.