Dr. Anup Sharma, Philadelphia PA - MD (Doctor of Medicine)
Specialties:
Psychiatry
Address:
3400 Spruce St, Philadelphia 19104 (215) 746-7222 (Phone)
Languages:
English
Education:
Medical School Perelman School of Medicine University of Pennsylvania Graduated: 2011
Short Interfering Rna And Micro-Rna Compounds And Methods Of Designing, Making, And Using The Same
US Patent:
2009001, Jan 8, 2009
Filed:
Oct 22, 2004
Appl. No.:
10/576481
Inventors:
Zissimos Mourelatos - Philadelphia PA, US Anup Sharma - Philadelphia PA, US Marianthi Kiriakidou - Philadelphia PA, US
International Classification:
A61K 31/7105, C40B 30/02, A61P 43/00, C07H 21/02
US Classification:
514 44, 506 8, 536 245
Abstract:
Methods of identifying, designing and synthesizing uniquely targeting siRNA nucleotide sequences for a target mRNA sequence of a target species are disclosed. Methods of identifying, designing and synthesizing miRNA nucleotide sequences that does not function as a siRNA nucleotide sequence for mRNA of a target species are disclosed. Method of inhibiting expression of a target mRNA molecule are disclosed sequence. siRNA molecules including uniquely targeting siRNA molecules and RISCs comprising the same are disclosed. miRNA molecules that do not function as siRNA nucleotide sequences for mRNA of a target species are disclosed.
Methods And Compositions For In-Vivo Enzyme Capture
US Patent:
2013004, Feb 14, 2013
Filed:
Sep 22, 2010
Appl. No.:
13/395362
Inventors:
James Eberwine - Philadelphia PA, US Ülo Langel - Bandhagen, SE Emelia Eiriksdóttir - Reykjavik, IS Anup Sharma - Philadelphia PA, US
International Classification:
G01N 33/573, C07K 19/00
US Classification:
435 74, 530324
Abstract:
The invention includes compositions, methods and kits for the in vivo identification of an enzyme that binds to a substrate. The invention comprises, in part, a photoreactive moiety to aid in identification of such an enzyme.