Inventors:
Lili Yang - Pasadena CA, US
David Baltimore - Pasadena CA, US
Pin Wang - Pasadena CA, US
James Economou - Pacific Palisades CA, US
Antoni Ribas - Los Angeles CA, US
International Classification:
A61K 45/00, C07H 21/00, C07K 14/00, C12N 5/06, C12N 15/87, A61P 43/00, A61K 39/00, C12N 7/00, A61K 35/12
US Classification:
424 852, 536 231, 530350, 435325, 4352351, 424 9321, 4241841, 435456
Abstract:
T-cell receptors that recognize MART-1 antigen are provided. The TCRs can be used, for example, to treat patients suffering from melanoma.