ANNETTE SUNHI KIM
Medical Practice in Harleysville, PA
License number
Pennsylvania MT183890
Category
Medicine
Type
Graduate Medical Trainee
Address
Address
Harleysville, PA 19438
Personal information
See more information about ANNETTE SUNHI KIM at radaris.comName
Address
Phone
2 Gladstone Rd, Wallingford, PA 19086
241 Acres Dr, Ridley Park, PA 19078
2410 Old Forty Foot Rd, Harleysville, PA 19438
2 Gladstone Rd, Nether Providence, PA 19086
225 Rock Hill Rd, Quakertown, PA 18951
Professional information
Tyrosine Kinase Inhibitors
US Patent:
7504429, Mar 17, 2009
Filed:
Jul 20, 2004
Appl. No.:
10/564347
Inventors:
Annette S. Kim - Harleysville PA, US
Xufang Zhang - Dresher PA, US
Xufang Zhang - Dresher PA, US
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
A61K 31/40, C07D 405/00
US Classification:
514423, 514422, 514365, 548517, 548533
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a substituted pyrrole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Tyrosine Kinase Inhibitors
US Patent:
7538231, May 26, 2009
Filed:
Jul 20, 2004
Appl. No.:
10/564030
Inventors:
Annette S. Kim - Harleysville PA, US
Assignee:
Merck & Co, Inc. - Rahway NJ
International Classification:
C07D 207/333
US Classification:
548536
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a substituted pyrrole moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Synthetic Lethal Screen Using Rna Interference
US Patent:
2005018, Aug 18, 2005
Filed:
Sep 22, 2004
Appl. No.:
10/947637
Inventors:
Peter Linsley - Seattle WA, US
Mao Mao - Redmond WA, US
Annette Kim - Harleysville PA, US
Stephen Friend - Philadelphia PA, US
Steven Bartz - Seattle WA, US
Michele Cleary - Bothell WA, US
Mao Mao - Redmond WA, US
Annette Kim - Harleysville PA, US
Stephen Friend - Philadelphia PA, US
Steven Bartz - Seattle WA, US
Michele Cleary - Bothell WA, US
International Classification:
C12Q001/68, C07H021/02, C12N015/85
US Classification:
435006000, 435455000, 536023100
Abstract:
The invention provides a method for identifying one or more genes in a cell of a cell type which interact with, e.g., modulate the effect of, an agent, e.g., a drug. For example, an identified gene may confer resistance or sensitivity to a drug, i.e., reduces or enhances the effect of the drug. The invention also provides STK6 and TPX2 as a gene that exhibits synthetic lethal interactions with KSP encoding a kinesin-like motor protein, and methods and compositions for treatment of diseases, e.g., cancers, by modulating the expression of STK6 or TPX2 gene and/or the activity of STK6 or TPX2 gene product. The invention also provides genes involved in cellular response to DNA damage, and their therapeutic uses.
Tyrosine Kinase Inhibitors
US Patent:
2005023, Oct 27, 2005
Filed:
Apr 8, 2003
Appl. No.:
10/510611
Inventors:
Annette Kim - Harleysville PA, US
Craig Stump - Pottstown PA, US
Christopher Dinsmore - Schwenksville PA, US
Samuel Graham - Schwenksville PA, US
Theresa Williams - Harleysville PA, US
Diem Nguyen - North Wales PA, US
B. Wesley Trotter - Glenside PA, US
Craig Stump - Pottstown PA, US
Christopher Dinsmore - Schwenksville PA, US
Samuel Graham - Schwenksville PA, US
Theresa Williams - Harleysville PA, US
Diem Nguyen - North Wales PA, US
B. Wesley Trotter - Glenside PA, US
International Classification:
C07D471/06, A61K031/473
US Classification:
514295000, 546097000, 546098000
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Tyrosine Kinase Inhibitors
US Patent:
2006016, Jul 27, 2006
Filed:
Apr 8, 2003
Appl. No.:
10/510609
Inventors:
Annette Kim - Harleysville PA, US
International Classification:
C07D 221/22, A61K 31/473
US Classification:
514295000, 546097000
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.
Tyrosine Kinase Inhibitors
US Patent:
2007017, Jul 26, 2007
Filed:
Apr 2, 2007
Appl. No.:
11/731908
Inventors:
Annette Kim - Harleysville PA, US
Craig Stump - Pottstown PA, US
Christopher Dinsmore - Schwenksville PA, US
Samuel Graham - Schwensville PA, US
Theresa Williams - Harleysville PA, US
Diem Nguyen - North Wales PA, US
B. Trotter - Glenside PA, US
Craig Stump - Pottstown PA, US
Christopher Dinsmore - Schwenksville PA, US
Samuel Graham - Schwensville PA, US
Theresa Williams - Harleysville PA, US
Diem Nguyen - North Wales PA, US
B. Trotter - Glenside PA, US
International Classification:
C07D 221/22, A61K 31/473
US Classification:
514295000, 546097000
Abstract:
The present invention relates to compounds that are capable of inhibiting, modulating and/or regulating signal transduction of both receptor-type and non-receptor type tyrosine kinases. The compounds of the instant invention possess a core structure that comprises a benzazocine moiety. The present invention is also related to the pharmaceutically acceptable salts, hydrates and stereoisomers of these compounds.