Inventors:
William H. Bowen - Victor NY, US
Anne Vacca Smith - Rochester NY, US
Robert Berkowitz - Pittsford NY, US
Assignee:
University of Rochester - Rochester NY
International Classification:
G01N 33/53, G01N 33/536, G01N 33/543, G01N 33/569, G01N 33/573, G01N 33/577, C07K 16/12, C07K 16/40, C12P 21/08
US Classification:
435 74, 435 734, 435 792, 435 795, 435 15, 435885, 436512, 436518, 436536, 436164, 436172, 53038826, 5303891, 530866
Abstract:
The present invention relates to antibodies, binding portions thereof, or probes that bind specifically to glucosyltransferase enzymes, and uses of these agents for detecting glucosyltransferase enzyme(s) in a sample and for diagnosing predisposition of a human child to early childhood caries. The present invention also relates to a kit for detecting a glucosyltransferase enzyme in an oral sample from an animal.