Inventors:
J. Venter - Rockville MD, US
Jinghui Zhang - Rockville MD, US
Xiangjun Liu - Olney MD, US
William Rowe - Rockville MD, US
Anibal Cravchik - Gaithersburg MD, US
Francis Kalush - Rockville MD, US
Ashwinikumar Naik - Gaithersburg MD, US
Gangadharan Subramanian - Columbia MD, US
Trevor Woodage - Washington DC, US
Assignee:
APPLERA CORPORATION (NY) - Norwalk CT
International Classification:
C12Q001/68, C07H021/04
Abstract:
The present invention is based on the discovery of novel polymorphisms (SNPs) in the genes known in the art to contribute to type II diabetes and obesity. Such polymorphisms can lead to a variety of disorders that are mediated/modulated by a variant type II diabetes and obesity associated protein. The present invention provides reagents used for detecting and expressing the variant nucleic acid/protein sequence as well as methods of identifying and using these variants.