Inventors:
Andrew P. Feinberg - Ann Arbor MI
Minoru Koi - Ypsilanti MI
Assignee:
Regents of the University of Michigan - Ann Arbor MI
International Classification:
C12N 1510, C12N 1511, C12N 1512
Abstract:
Superfragments of chromosomal DNA having 1 million to 100 million base pairs may be formed by irradiating microcells containing a chromosome with a high dose of. gamma. -irradiation. Such superfragments are useful for the rapid cloning of genes.