Inventors:
Hui Cai - San Diego CA, US
Frank Chavez - Camarillo CA, US
Paul J. Dunford - Soiana Beach CA, US
Andrew J. Greenspan - San Diego CA, US
Steven P. Meduna - San Diego CA, US
Jorge A. Quiroz - Princeton NJ, US
Brad M. Savall - San Diego CA, US
Kevin L. Tays - Cardiff by the Sea CA, US
Robin L. Thurmond - San Diego CA, US
Jianmei Wei - San Diego CA, US
Ronald L. Wolin - San Diego CA, US
Xiaohu Zhang - Beijing, CN
International Classification:
A61K 31/4439, C07D 401/04, C07D 405/14, A61K 31/496, C07D 403/04, A61K 31/506, C07D 401/14, A61K 31/501, C07D 487/04, A61K 31/551, A61K 31/444, C07D 237/20, A61K 31/50, A61P 29/00, A61P 37/08, A61P 17/00, A61P 37/06, A61P 37/04, A61P 11/06, A61P 9/10, A61P 25/00, A61P 27/02, A61P 1/00, A61P 17/06, A61P 17/04, A61P 11/00, A61P 3/10, A61P 13/12, A61P 7/06, A61P 1/16, A61P 25/24, A61P 25/18, A61P 25/22, A61P 25/04
US Classification:
5142102, 5462791, 514343, 544360, 51425301, 544323, 514275, 544295, 51425214, 544324, 5142522, 544238, 51425205, 51425202, 540575, 514218, 546256, 514333, 544224, 514247
Abstract:
Diamino-pyridine, pyrimidine and pyridazine compounds which may be used as Hreceptor modulators, and in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by Hreceptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.