Inventors:
Vijaykumar Ramiya - Gainesville FL, US
Amy Clark - Gainesville FL, US
Assignee:
Ixion Biotechnology, Inc. - Alachua FL
International Classification:
C12N 5/00, C12N 5/02, A01N 63/00, A01N 65/00
US Classification:
435325, 435405, 435375, 424 931
Abstract:
The subject invention comprises culture methods for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway. It also concerns the endocrine hormones that can be produced by such cultures, and the use of the transdifferentiated cells in the treatment of pancreatic diseases.