Inventors:
Hermona Soreq - Jerusalem, IL
Raz Yirmiya - Jerusalem, IL
Amir Dori - Clayton MO, US
Gal Ifergane - Omer, IL
Michal Ivri - Tel Aviv, IL
International Classification:
A61K 31/7105, A61P 25/00, A61P 29/00, A61P 27/02, A61P 1/04, A61P 17/00, A61P 13/00, A61P 25/02, A61P 37/00, A61P 1/00, A61P 11/00
Abstract:
Disclosed is a novel use for AChE antisense oligonucleotides as anti-inflammatory agents, wherein said oligonucleotides are preferably as denoted by SEQ ID NO:1, SEQ ID NO:2 and SEQ ID NO:7. Methods of treatment of inflammatory conditions, as well as fever, and particularly inflammation-associated neuropathies such as Guillain-Barré Syndrome, are described.