Inventors:
Allan Lipton - Hershey PA
Nancy Kepner - Port Royal PA
Assignee:
Research Corporation - New York NY
International Classification:
A61K 3702, C07G 700, C12N 500, C12P 2100
Abstract:
A purified cell growth factor is produced which comprises a substantially purified glycoproteinaceous factor from platelets which has mitogenic activity toward transformed cells, a molecular weight of 3,000-5,000 daltons and a pI of 7. 8-8. 3. The growth factor is stable to treatment with 4M guanidine hydrochloride, and is heat labile when treated at 100. degree. C. for 5 minutes.