Inventors:
Alice T. Shaw - Chestnut Hill MA, US
Tyler E. Jacks - West Newton MA, US
Nicola Tolliday - Jamaica Plain MA, US
Assignee:
Massachusette Institute of Technology - Cambridge MA
International Classification:
A61K 31/4453, A61K 31/40, A61K 31/5375, C07D 211/32, C07D 265/30, A61P 35/00
US Classification:
5142388, 514317, 514428, 546237, 544175
Abstract:
The invention provides compositions and methods for treating cancer. Aspects of the invention relate to therapeutic compositions comprising tolperisone and related compounds. Aspects of the invention relate to methods and compositions for treating Ras-associated cancers.