Inventors:
Scott Panzer - Sunnyvale CA, US
Peter Spiro - Palo Alto CA, US
Steven Banville - Palo Alto CA, US
Purvi Shah - San Jose CA, US
Michael Chalup - Sunnyvale CA, US
Simon Chang - Mountain View CA, US
Alice Chen - San Jose CA, US
Steven D'Sa - East Palo CA, US
Stefan Amshey - San Francisco CA, US
Christopher Dahl - Fremont CA, US
Tam Dam - San Jose CA, US
Susan Daniels - Palo Alto CA, US
Gerard Dufour - Castro Valley CA, US
Vincent Flores - Union City CA, US
Willy Fong - San Francisco CA, US
Lila Greenawalt - San Jose CA, US
Jennifer Jackson - Mountain View CA, US
Anissa Jones - San Jose CA, US
Tommy Liu - Daly City CA, US
Ann Lincoln - Redwood City CA, US
Bruce Rosen - Menlo Park CA, US
Frank Russo - Rossette Court Sunnyvale CA, US
Theresa Stockdreher - Sunnyvale CA, US
Abel Daffo - San Jose CA, US
Rachel Wright - Mountain View CA, US
Pierre Yap - Lafayette CA, US
Jimmy Yu - Fremont CA, US
Diana Bradley - Soquel CA, US
Shawn Bratcher - Mountain View CA, US
Wensheng Chen - Mountain View CA, US
Howard Cohen - Palo Alto CA, US
David Hodgson - Ann Arbor MI, US
Stephen Lincoln - Redwood City CA, US
Stuart Jackson - Mountain View CA, US
International Classification:
C12Q001/68, C07H021/04, C07K014/47, A61K038/17
US Classification:
435/006000, 435/069100, 435/320100, 435/325000, 530/350000, 536/023500
Abstract:
The present invention provides purified human polynucleotides for diagnostics and therapeutics (dithp). Also encompassed are the polypeptides (DITHP) encoded by dithp. The invention also provides for the use of dithp, or complements, oligonucleotides, or fragments thereof in diagnostic assays. The invention further provides for vectors and host cells containing dithp for the expression of DITHP. The invention additionally provides for the use of isolated and purified DITHP to induce antibodies and to screen libraries of compounds and the use of anti-DITHP antibodies in diagnostic assays. Also provided are microarrays containing dithp and methods of use.