Inventors:
Beverly E. Barton - West Orange NJ, US
H. Dan Lewis - Orange NJ, US
Robert J. Donnelly - Fords NJ, US
Ali Husain - Voorhees NJ, US
Dimitrios Barlos - Newark NJ, US
Sheraz Riaz - Nutley NJ, US
Assignee:
University of Medicine and Dentistry of New Jersey - Somerset NJ
International Classification:
A61K 38/10, A61K 38/04, C12N 5/00, C12N 5/02, C07K 5/00, C07K 7/00, C07K 16/00, C07K 17/00
Abstract:
Disclosed herein are novel glutamate-enhanced cell-penetrating peptides (CPPs) for use as delivery vehicles to mediate intracellular uptake of therapeutic payloads and methods of using the same.