ALEXIA L MCKNIGHT
Veterinary in Delaware

License number
Pennsylvania BV010128
Category
Veterinary Medicine
Type
Veterinarian
Address
Address 2
Delaware
Chadds Ford, PA 19317

Professional information

Alexia Mcknight Photo 1

Method For Mri Scanning Of Animals For Transmissible Spongiform Encephalopathies

US Patent:
2006018, Aug 17, 2006
Filed:
Feb 1, 2006
Appl. No.:
11/346083
Inventors:
Lawrence Minkoff - Lattingtown NY, US
Joel Stutman - Farmingdale NY, US
Alexia McKnight - Chadds Ford PA, US
International Classification:
A61B 5/05
US Classification:
600410000, 600409000
Abstract:
A method for detecting the presence of various transmissible spongiform encephalopathy (TSE) in mammals is provided. Steps include taking a magnetic resonance imaging (MRI) image of the brain of the mammal, selecting a section within the image, determining a measurement of a first brain structure in the section, and determining a measurement of a second brain structure in the section. The ratio of the measurements is calculated and used to determine the probability that the mammal has a TSE. Areas and/or volumes of the first and second brain structures may be used. In one embodiment, the image section is sagittal or axial. An embodiment uses the lateral ventricle or frontal lobe as the first brain structure, and the cerebrum as the second brain structure. The method of determining the areas and volumes of the brain structures is provided. MRIs that can be used along with the MRI parameters are provided.